ChemicalBook > CAS DataBase List > 2,3-DCPE HYDROCHLORIDE
2,3-DCPE HYDROCHLORIDE
- Product Name
- 2,3-DCPE HYDROCHLORIDE
- CAS No.
- 418788-90-6
- Chemical Name
- 2,3-DCPE HYDROCHLORIDE
- Synonyms
- 2,3-DCPE;2,3-DCPEHCl;3-DCPE hydrochloride;2,3-DCPE HYDROCHLORIDE;2,3 DCPE hydrochloride,2,3DCPE hydrochloride;2-[3-(2,3-dichlorophenoxy)propylamino]ethanol;Ethanol, 2-[[3-(2,3-dichlorophenoxy)propyl]amino]-;2-[[3-(2,3-DICHLOROPHENOXY)PROPYL]AMINO]ETHANOL HYDROCHLORIDE
- CBNumber
- CB6373869
- Molecular Formula
- C11H15Cl2NO2
- Formula Weight
- 264.15
- MOL File
- 418788-90-6.mol
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2,3-DCPE HYDROCHLORIDE Property
- Boiling point:
- 402.9±40.0 °C(Predicted)
- Density
- 1.259±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at -20°C
- solubility
- 20 mg/ml in DMSO
- pka
- 14.78±0.10(Predicted)
- form
- Powder
- Water Solubility
- Soluble in water at ~25 mg/ml. Also soluble in ethanol, DMSO or DMF at ~20mg/ml. Soluble in PBS, pH 7.2 at ~10 mg/ml.
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N-Bromosuccinimide Price
Tocris
- Product number
- 2137
- Product name
- 2,3-DCPEhydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $107
- Updated
- 2021/12/16
Tocris
- Product number
- 2137
- Product name
- 2,3-DCPEhydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $450
- Updated
- 2021/12/16
Usbiological
- Product number
- 254376
- Product name
- 2,3-DCPE hydrochloride
- Packaging
- 10mg
- Price
- $339
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A4447
- Product name
- 2,3-DCPEhydrochloride
- Packaging
- 10mg
- Price
- $77
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A4447
- Product name
- 2,3-DCPEhydrochloride
- Packaging
- 50mg
- Price
- $321
- Updated
- 2021/12/16
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2,3-DCPE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
2,3-DCPE induces apoptosis and downregulates Bcl-XL expression. 2,3-DCPE has anti-tumor activity and can be used in cancer research[1].
Biological Activity
Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro . IC 50 values are 0.89 and 12.6 μ M for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.
References
[1] Wu S, et al. Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol. Cancer Res. 2004 Feb 1;64(3):1110-3. DOI:10.1158/0008-5472.can-03-2790
2,3-DCPE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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2,3-DCPE HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77