2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol

Product Name: 2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol
CAS No.: 692269-09-3
Chemical Name: 2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol
Synonyms: CM10;CM10 ，S0522;CM10, 10 mM in DMSO;2-Allyl-6-(((1-propyl-1H-benzo[d]imidazol-2-yl)amino)methyl)phenol;2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol;2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol;Phenol, 2-(2-propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]-;ALDH1A3,Aldehyde Dehydrogenase (ALDH),Inhibitor,metabolism,anti-cancer,Aldehyde,inhibit,dehydrogenase,ALDH1A2,CM10,ALDH1A1,ALDH1Ai,CM-10
CBNumber: CB63802124
Molecular Formula: C20H23N3O
Formula Weight: 321.42
MOL File: 692269-09-3.mol

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2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol Property

Boiling point:: 512.4±52.0 °C(Predicted)
Density: 1.12±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMSO: 125 mg/mL (388.90 mM)
form: A solid
pka: 10.10±0.35(Predicted)
color: Light green to green

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 6933
Product name: CM10
Purity: ≥98%(HPLC)
Packaging: 50
Price: $669
Updated: 2021/12/16

ChemScene

Product number: CS-0114373
Product name: CM10
Purity: 99.53%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0114373
Product name: CM10
Purity: 99.53%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0046707
Product name: CM10
Purity: 95.00%
Packaging: 5MG
Price: $457.03
Updated: 2021/12/16

ChemScene

Product number: CS-0114373
Product name: CM10
Purity: 99.53%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

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2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol Chemical Properties,Usage,Production

Uses

CM010 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM010 does not inhibit any of the other ALDH family members. CM010 can regulate metabolism and has anti-cancer activity[1].

IC 50

ALDH1

storage

Store at -20°C

References

[1] Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. DOI:10.1016/j.celrep.2019.02.032

2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol Suppliers

China 31 Finland 1 Russia 1 United States 5 Global 38

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692269-09-3, 2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenolRelated Search:

2-(prop-2-en-1-yl)-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol

CM10

Phenol, 2-(2-propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]-

2-Allyl-6-(((1-propyl-1H-benzo[d]imidazol-2-yl)amino)methyl)phenol

ALDH1A3,Aldehyde Dehydrogenase (ALDH),Inhibitor,metabolism,anti-cancer,Aldehyde,inhibit,dehydrogenase,ALDH1A2,CM10,ALDH1A1,ALDH1Ai,CM-10

CM10, 10 mM in DMSO

CM10 ，S0522

2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol

692269-09-3