ChemicalBook > CAS DataBase List > 13(R)-HODE

13(R)-HODE

Product Name
13(R)-HODE
CAS No.
10219-69-9
Chemical Name
13(R)-HODE
Synonyms
13(R)-HODE;Coriolic acid;13(R) HODE,13(R)HODE;HNICUWMFWZBIFP-PIHGWCCBSA-N;13(R)-hydroxy-9,11-octadienoic acid;13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID;(R-(E,Z))-13-Hydroxy-9,11-octadecadienoic acid;(R,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid;9,11-Octadecadienoic acid, 13-hydroxy-, (R-(E,Z))-;9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)-
CBNumber
CB6395450
Molecular Formula
C18H32O3
Formula Weight
296.44
MOL File
10219-69-9.mol
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13(R)-HODE Property

Boiling point:
422.7±20.0 °C(Predicted)
Density 
0.970±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka
4.78±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
38605
Product name
13(R)-HODE
Purity
≥98%
Packaging
25μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
38605
Product name
13(R)-HODE
Purity
≥98%
Packaging
50μg
Price
$137
Updated
2024/03/01
Cayman Chemical
Product number
38605
Product name
13(R)-HODE
Purity
≥98%
Packaging
100μg
Price
$238
Updated
2024/03/01
Cayman Chemical
Product number
38605
Product name
13(R)-HODE
Purity
≥98%
Packaging
250μg
Price
$553
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CCH0004495
Product name
13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.62
Updated
2021/12/16
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13(R)-HODE Chemical Properties,Usage,Production

Description

13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50 = 2.7 μM) inhibitor of U-46619-induced platelet aggregation.2

Definition

ChEBI: 13(R)-HODE is a 13-HODE in which the stereocentre at position 13 has S-configuration. It is a conjugate acid of a 13(R)-HODE(1-).

References

1. Baer, A.N., Costello, P.B., and Green, F.A. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells Biochim. Biophys. Acta 1085(1),45-52(1991).
2. Lagarde, M., Boutillon, M.M., Guichardant, M., et al. Further studies on the anti-thromboxane A2 activity of monohydroxylated fatty acids Biochem. Pharmacol. 38,1863-1864(1989).

13(R)-HODE Preparation Products And Raw materials

Raw materials

Preparation Products

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13(R)-HODE Suppliers

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10219-69-9, 13(R)-HODERelated Search:


  • 13(R)-HODE
  • 13R-HYDROXY-9Z,11E-OCTADECADIENOIC ACID
  • (R,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid
  • Coriolic acid
  • (R-(E,Z))-13-Hydroxy-9,11-octadecadienoic acid
  • 9,11-Octadecadienoic acid, 13-hydroxy-, (R-(E,Z))-
  • 13(R)-hydroxy-9,11-octadienoic acid
  • HNICUWMFWZBIFP-PIHGWCCBSA-N
  • 9,11-Octadecadienoic acid, 13-hydroxy-, (9Z,11E,13R)-
  • 13(R) HODE,13(R)HODE
  • 10219-69-9