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N-FORMYL-L-LEUCINE

Product Name
N-FORMYL-L-LEUCINE
CAS No.
6113-61-7
Chemical Name
N-FORMYL-L-LEUCINE
Synonyms
NSC 334321;FOR-LEU-OH;For-L-Leu-OH;N-Formylleucine;N-ForMyl-Leu-OH;FORMYL-L-ALANINE;FORMYL-L-LEUCINE;N-Formyl-L-leucin;N-FORMYL-L-LEUCINE;N-Formyl-S-leucine
CBNumber
CB6399029
Molecular Formula
C7H13NO3
Formula Weight
159.18
MOL File
6113-61-7.mol
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N-FORMYL-L-LEUCINE Property

Melting point:
142 °C
Boiling point:
284.67°C (rough estimate)
Density 
1.2013 (rough estimate)
refractive index 
-39.5 ° (C=1, H2O)
storage temp. 
-20°C
solubility 
Ethanol (Sparingly), Methanol (Slightly)
form 
powder
pka
3.51±0.21(Predicted)
color 
white
Water Solubility 
29.45g/L(temperature not stated)
InChI
InChI=1S/C7H13NO3/c1-5(2)3-6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1
InChIKey
HFBHOAHFRNLZGN-LURJTMIESA-N
SMILES
C(O)(=O)[C@H](CC(C)C)NC=O
CAS DataBase Reference
6113-61-7(CAS DataBase Reference)
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Safety

WGK Germany 
1
HazardClass 
IRRITANT
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
759945
Product name
N-Formyl-Leu-OH
Purity
90%
Packaging
1g
Price
$60
Updated
2023/01/07
TCI Chemical
Product number
F0131
Product name
N-Formyl-L-leucine
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
F0131
Product name
N-Formyl-L-leucine
Packaging
5g
Price
$82
Updated
2025/07/31
TRC
Product number
F700560
Product name
N-Formyl-L-leucine
Packaging
5g
Price
$195
Updated
2021/12/16
Usbiological
Product number
012570
Product name
N-Formyl-L-leucine
Packaging
1g
Price
$418
Updated
2021/12/16
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N-FORMYL-L-LEUCINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A synthetic substrate of the lipase inhibitor lipstatin.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-18-6

760-84-9

5338-45-4

General procedure: L-leucine hydrochloride (1 eq.), formic acid (5 eq.), sodium bicarbonate (10 eq.) and glycerol ketone-oxide 1 (2 eq.) were dissolved in H2O (0.2-0.3 M), followed by the addition of EDCI (2 eq.). The reaction mixture was stirred for 3 h. Upon completion of the reaction, it was quenched with 1% HCl aqueous solution. The aqueous phase was extracted with EtOAc (or CHCl3, or CHCl3-MeOH (10/1). The organic extracts were combined and dried with Na2SO4, followed by vacuum evaporation of the solvent. Purification by silica gel chromatography (or Sephadex LH20) afforded N-formyl-DL-leucine (see Table 1 for yields). Similarly, the N-formylation reaction was carried out using oxide 1 in DMF-H2O (9/1).

References

[1] Tetrahedron Letters, 2013, vol. 54, # 16, p. 2077 - 2081

N-FORMYL-L-LEUCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-FORMYL-L-LEUCINE Suppliers

Americas 1 Canada 1 China 160 Europe 2 France 2 Germany 4 India 10 Italy 2 Japan 3 Switzerland 6 United Kingdom 10 United States 22 Global 223
C-LAB Chemievermittlung Gmbh
Tel
--
Fax
--
Country
Germany
ProdList
17
Advantage
58
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from N-FORMYL-L-LEUCINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
N-FORMYL-L-LEUCINE 6113-61-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98
Supply Ability
10000KGS
Release date
2025-11-26
Hebei Zhuanglai Chemical Trading Co Ltd
Product
N-FORMYL-L-LEUCINE 6113-61-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-05
Zhengzhou Anbu Chem Co.,Ltd
Product
N-FORMYL-L-LEUCINE 6113-61-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KGS
Release date
2023-04-26

6113-61-7, N-FORMYL-L-LEUCINERelated Search:

[2R-[1(S*),2R*,3S*]]- N-Formyl-L-Leucine 1-[3-Carboxy-2-hydroxynonyl]dodecyl Ester,N-Formyl-L-leucine (1S)-1-[(2S,3S)-3-carboxy-2-hydroxynonyl]dodecyl Ester AHLBNYSZXLDEJQ-FICKONGGSA-N Orlistat Impurity 32 (S,S,R,S)-Orlistat N-ForMyl-L-leucine [S-(E)]-1-(2-Nonenyl)dodecyl Ester Orlistat Tetradecyl Ester Isopentyl (2R)-Orlistat Tetradecyl Ester [2S-[2α(R*),3β]]-N-ForMyl- (2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid (Orlistat Impurity) N-ForMyl- Orlistat Impurity 23 (3S,4S)-3-Hexyl-4-[(S)-2-hydroxytridecyl]-2-oxetanone AHLBNYSZXLDEJQ-HDVRVJOHSA-N Orlistat Impurity 31 Lipstatin (2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid Orlistat Dimer Impurity Diisopropyl azodicarboxylate

  • N-ALPHA-FORMYL-L-LEUCINE
  • N-FORMYL-L-LEUCINE
  • FOR-LEU-OH
  • FORMYL-L-LEUCINE
  • FORMYL-L-ALANINE
  • N-Formylleucine
  • N-Formyl-S-leucine
  • NSC 334321
  • N-FORMYL-L-LEUCINE 99+%
  • N-Formyl-L-leucin
  • (2S)-2-formamido-4-methylpentanoic acid
  • N-ForMyl-Leu-OH
  • Orlistat ForMyl IMpurity
  • (2S)-2-(Formylamino)-4-methylpentanoic acid
  • (S)-2-(Formylamino)-4-methylpentanoic acid
  • 2-formamido-4-methylpentanoic acid
  • 2-formamido-4-methyl-pentanoic acid
  • 2-formamido-4-methyl-valeric acid
  • N-ForMyl-L-leucine, tech. 90%
  • N-Formyl-Leu-OH 90%
  • For-L-Leu-OH
  • (S)-2-forMaMido-4-Methylpentanoic acid
  • L-Leucine, N-forMyl-
  • N-Formyl-L-leucine（N-Formyl-Leu-OH）
  • Orlistat Impurity 24（N-Formyl-L-leucine）
  • N-FORMYL-L-LEUCINE USP/EP/BP
  • N-α-Formyl-L-leucine
  • Orlistat Impurity 46
  • <i>N</i>-Formyl-Leu-OH
  • 6113-61-7
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • Modified Amino Acids
  • A - H
  • A - H
  • Amino Acids
  • Modified Amino Acids
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Chiral Reagents
  • AMINOACIDS DERIVATIVES