5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID
- Product Name
- 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID
- CAS No.
- 98434-06-1
- Chemical Name
- 5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID
- Synonyms
- 109088;AKOS B022856;AKOS PAO-1387;AKOS BBS-00006855;TIMTEC-BB SBB007153;ART-CHEM-BB B022856;5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID;5-(2-furyl)-3-isoxazolecarboxylic acid;5-FURAN-2-YL-ISOXAZOLE-3-CARBOXYLIC ACID;5-(2-furanyl)-3-isoxazolecarboxylic acid
- CBNumber
- CB6402178
- Molecular Formula
- C8H5NO4
- Formula Weight
- 179.13
- MOL File
- 98434-06-1.mol
5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID Property
- Melting point:
- 151 °C
- Boiling point:
- 418.4±35.0 °C(Predicted)
- Density
- 1.420±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- pka
- 3.33±0.10(Predicted)
- Appearance
- White to yellow Solid
- CAS DataBase Reference
- 98434-06-1(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 22-26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2932190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- F864108
- Product name
- 5-Furan-2-yl-isoxazole-3-carboxylicacid
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F864108
- Product name
- 5-Furan-2-yl-isoxazole-3-carboxylicacid
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- F864108
- Product name
- 5-Furan-2-yl-isoxazole-3-carboxylicacid
- Packaging
- 2.5g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 063353
- Product name
- 5-(2-Furyl)isoxazole-3-carboxylic acid
- Packaging
- 500mg
- Price
- $39
- Updated
- 2021/12/16
- Product number
- 4H21-1-2G
- Product name
- 5-(2-Furyl)isoxazole-3-carboxylic acid
- Packaging
- 1g
- Price
- $92
- Updated
- 2021/12/16
5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
33545-40-3
98434-06-1
General procedure for the synthesis of 5-(2-furanyl)isoxazole-3-carboxylic acid from ethyl 5-(furan-2-yl)isoxazole-3-carboxylate: 1N aqueous lithium hydroxide solution (80 mL) was slowly added to a mixed solution of THF (130 mL) and methanol (25 mL) containing ethyl 5-(furan-2-yl)isoxazole-3-carboxylate (4.14 g). The reaction mixture was stirred at room temperature for 15 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was acidified by adding 1N hydrochloric acid to the residue until a solid precipitated. The solid product was collected by filtration and washed with distilled water. After drying, 3.22 g of 5-(2-furyl)isoxazole-3-carboxylic acid (yield: 90%) was obtained as a white solid. [178] 1H-NMR (acetone-d6, 200 MHz) δ: 7.90-7.86 (m, 1H), 7.19 (d, 1H), 7.00 (s, 1H), 6.77-6.73 (m, 1H).
References
[1] Patent: WO2009/5269, 2009, A2. Location in patent: Page/Page column 18
[2] Patent: US2009/131336, 2009, A1. Location in patent: Page/Page column 12
[3] Patent: WO2007/78113, 2007, A1. Location in patent: Page/Page column 36
[4] Gazzetta Chimica Italiana, 1958, vol. 88, p. 879,896
5-(2-FURYL)ISOXAZOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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