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Nicotine ditartrate

Product Name
Nicotine ditartrate
CAS No.
65-31-6
Chemical Name
Nicotine ditartrate
Synonyms
NICOTINE BITARTRATE;Salt Nicotine;NicotinbitartrateDihydrate;nikotinbitartrat;NICOTINE TARTRATE;tartratedenicotine;Nicotine Difartrate;nicotineacidtartrate;(-)-Nicotine ditatrate;nicotine,tartrate(1:2)
CBNumber
CB6403397
Molecular Formula
C18H26N2O12
Formula Weight
462.41
MOL File
65-31-6.mol
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Nicotine ditartrate Property

Melting point:
90°
alpha 
D20 +26° (c = 10)
storage temp. 
Desiccate at RT
solubility 
H2O: 50 mg/mL
form 
powder
color 
white to off-white
optical activity
[α]/D +20 to +26°, c = 1.0 in water
InChIKey
RFEJUZJILGIRHQ-UHFFFAOYSA-N
CAS DataBase Reference
65-31-6(CAS DataBase Reference)
EPA Substance Registry System
Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (65-31-6)
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Safety

Hazard Codes 
T+,N
Risk Statements 
26/27/28-51/53
Safety Statements 
13-28-45-61
RIDADR 
UN 1659 6.1/PG 2
WGK Germany 
2
RTECS 
QT0350000
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
65-31-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001023
Product name
Nicotine for system suitability
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
1 mg
Price
$236
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1236
Product name
(?)-Nicotine hydrogen tartrate salt
Purity
≥98% (HPLC)
Packaging
1g
Price
$1311
Updated
2025/07/31
Sigma-Aldrich
Product number
PHL80224
Product name
Nicotine ditartrate
Purity
phyproof? Reference Substance
Packaging
100mg
Price
$319
Updated
2025/07/31
Sigma-Aldrich
Product number
N0590200
Product name
Nicotine ditartrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
120 mg
Price
$236
Updated
2025/07/31
Sigma-Aldrich
Product number
481975
Product name
(--)-Nicotine, Ditartrate
Purity
Potent agonist of the nicotinic acetylcholine receptor.
Packaging
100mg
Price
$70.9
Updated
2025/07/31
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Nicotine ditartrate Chemical Properties,Usage,Production

Uses

nicotinyl acetylchloline receptor agonist, ectoparasiticide

Uses

cathartic, laxative

General Description

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

Biological Activity

Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .

Biochem/physiol Actions

Product does not compete with ATP.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and CO. See also NICOTINE.

storage

Desiccate at RT

Nicotine ditartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Nicotine ditartrate Suppliers

China 69 Europe 2 France 2 Germany 2 India 5 Switzerland 1 United Kingdom 5 United States 25 Global 111
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
MDA Chemicals Ltd.
Tel
--
Fax
--
Email
sheila@mda-chem.co.uk
Country
United Kingdom
ProdList
1961
Advantage
30
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
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View Lastest Price from Nicotine ditartrate manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Nicotine ditartrate 65-31-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Nicotine ditartrate 65-31-6
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-12
Hubei XinRunde Chemical Co., Ltd.
Product
Nicotine ditartrate 65-31-6
Price
US $200.00/KG
Min. Order
10G
Purity
99%
Supply Ability
10MT
Release date
2018-03-09

65-31-6, Nicotine ditartrateRelated Search:

L-Carnitine-L-tartrate Pyridine D(-)-Tartaric acid Metoprolol tartrate L(+)-Tartaric acid Povidone iodine Nicotinic acid Polyvinylpyrrolidone N-Vinyl-2-pyrrolidone N-Methyl-2-pyrrolidone Pyrrolidine Dibenzoyltartaric acid METHYL-2-PYRROLIDONE Nicotine (+)-NICOTINE NICOTINE BI-L-(+)-TARTRATE Nicotine ditartrate

  • (-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt
  • (-)-Nicotine/L-Tartaric acid,(1:2)
  • (S)-Nicotine/(2R,3R)-Tartaric acid,(1:2)
  • 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate
  • (-)-Nicotine dirartate
  • (S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine(+)-ditartratesalt
  • Nicotine Bitartrate anhydrous
  • (-)-Nicotine ditatrate
  • (-)-nicotinehydrogentartrate
  • nicotine,tartrate(1:2)
  • nicotineacidtartrate
  • nicotinehydrogentartrate
  • nikotinbitartrat
  • nicotine dihydrogen ditartrate
  • NicotinbitartrateDihydrate
  • Nicotineditartaratedihydrate
  • (2R,3R)-2,3-dihydroxybutanedioic acid:3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
  • (--)-Nicotine, Ditartrate - CAS 65-31-6 - Calbiochem
  • Nicotine Difartrate
  • Nicotine Salt Benzoate
  • pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutane
  • pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutanedi
  • tartratedenicotine
  • tartratedenicotine(french)
  • (-)-1-METHYL-2-[3-PYRIDYL]PYRROLIDINE DI-(+) TARTRATE SALT
  • (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, DI-D-TARTRATE
  • (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE TARTRATE SALT
  • (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE, DI-D-TARTRATE
  • (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE TARTRATE SALT
  • NICOTINE TARTRATE
  • (-)-NICOTINE TARTRATE SALT
  • NICOTINE BI-L-(+)-TARTRATE
  • NICOTINE BITARTRATE
  • NICOTINE HYDROGEN-L-TARTRATE
  • (-)-NICOTINE HYDROGEN TARTRATE SALT
  • (-)-NICOTINE, DITARTRATE
  • Salt Nicotine
  • Nicotine ditartrate dihydrate CRS
  • Nicotine ditartrate CRS
  • Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2)
  • Nicotine for system suitability (Y0001023)Q: What is Nicotine for system suitability (Y0001023) Q: What is the CAS Number of Nicotine for system suitability (Y0001023) Q: What are the applications of Nicotine for system suitability (Y0001023)
  • L-tartrate nicotine salt
  • L-tartrate nicotinic salt
  • Nicotine ditartrate-RM
  • (-)-Nicotine ditartrate, nicotinic acetylcholine receptor agonist
  • (--)-Nicotine, Ditartrate
  • (?)-Nicotine ditartrate
  • 65-31-6
  • C18H26N2O12
  • Pyridine Alkaloids
  • Alkaloids
  • Ion Channels
  • Ligand-Gated Ion Channels
  • Nicotinic Acetylcholine Receptor Modulators
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • EXLAX