SJA6017

Product Name: SJA6017
CAS No.: 190274-53-4
Chemical Name: SJA6017
Synonyms: SJA6017;Calpain-In-4;Calpain Inhibitor 4;CALPAIN INHIBITOR VI;4-FLUORO-BENZENESULFONYL-VAL-L-LEUCINAL;4-FLUORO-BENZENESULFONYL-VAL-LEU-ALDEHYDE;N-(4-FLUOROPHENYLSULFONYL)-L-VALYL-L-LEUCINAL;SJA6017, 4-Fluoro-benzenesulfonyl-Val-L-leucinal;Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde;Butanamide, 2-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-, (2S)-
CBNumber: CB6427018
Molecular Formula: C17H25FN2O4S
Formula Weight: 372.45
MOL File: 190274-53-4.mol

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SJA6017 Property

Density: 1.185±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 5 mg/ml
form: A lyophilized solid
pka: 9.04±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23942
Product name: Calpain Inhibitor VI
Purity: ≥95%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FC111099
Product name: Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde
Packaging: 500ug
Price: $135
Updated: 2021/12/16

AK Scientific

Product number: 0719DA
Product name: CalpainInhibitorVI
Packaging: 1mg
Price: $179
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC111099
Product name: Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde
Packaging: 1mg
Price: $236
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000054
Product name: SJA6017
Purity: 95.00%
Packaging: 1MG
Price: $722.8
Updated: 2021/12/16

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SJA6017 Chemical Properties,Usage,Production

Description

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases μ-calpain (calpain-1; IC₅₀ = 7.5 nM) and m-calpain (calpain-2; IC₅₀ = 78 nM). It also inhibits cathepsins B and L (IC₅₀s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine proteases, factor VIIa, factor Xa, trypsin, chymotrypsin, and proteasome. In an in vitro porcine model of cataract, calpain inhibitor VI decreases the degree of cataract by 40% when used at a concentration of 0.8 μM. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Calpain inhibitor VI improves functional outcome and reduces apoptotic cell death in a rat model of spinal cord injury.

SJA6017 Preparation Products And Raw materials

Raw materials

Preparation Products

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SJA6017 Suppliers

China 30 United Kingdom 2 United States 8 Global 40

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190274-53-4, SJA6017Related Search:

SJA6017

N-(4-FLUOROPHENYLSULFONYL)-L-VALYL-L-LEUCINAL

4-FLUORO-BENZENESULFONYL-VAL-LEU-ALDEHYDE

4-FLUORO-BENZENESULFONYL-VAL-L-LEUCINAL

CALPAIN INHIBITOR VI

SJA6017, 4-Fluoro-benzenesulfonyl-Val-L-leucinal

Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde

Calpain Inhibitor 4

Calpain-In-4

Butanamide, 2-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-, (2S)-

190274-53-4