H-ARG-GLN-OH HYDROCHLORIDE SALT

Product Name: H-ARG-GLN-OH HYDROCHLORIDE SALT
CAS No.: 2483-17-2
Chemical Name: H-ARG-GLN-OH HYDROCHLORIDE SALT
Synonyms: Arg-Gln;H-Arg-Gln-OH;H-ARG-GLN-OH HCL;Arginyl-Glutamine;L-Glutamine, L-arginyl-;H-ARG-GLN-OH HYDROCHLORIDE SALT;(S)-5-Amino-2-((S)-2-amino-5-guanidinopentanamido)-5-oxopentanoic acid
CBNumber: CB6429890
Molecular Formula: C11H22N6O4
Formula Weight: 302.33
MOL File: 2483-17-2.mol

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H-ARG-GLN-OH HYDROCHLORIDE SALT Property

storage temp.: -15°C
Sequence: Arg-Gln

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FA108287
Product name: H-Arg-Gln-OH hydrochloride salt
Packaging: 250mg
Price: $135
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108287
Product name: H-Arg-Gln-OH hydrochloride salt
Packaging: 500mg
Price: $235
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108287
Product name: H-Arg-Gln-OH hydrochloride salt
Packaging: 1g
Price: $410
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108287
Product name: H-Arg-Gln-OH hydrochloride salt
Packaging: 2g
Price: $697
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA108287
Product name: H-Arg-Gln-OH hydrochloride salt
Packaging: 5G
Price: $1515.2
Updated: 2021/12/16

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H-ARG-GLN-OH HYDROCHLORIDE SALT Chemical Properties,Usage,Production

Uses

Arginyl-Glutamine is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy[1].

Definition

ChEBI: Arg-Gln is a dipeptide formed from L-arginyl and L-glutamine residues. It has a role as a metabolite.

in vivo

Arginyl-Glutamine (1-5 g/kg/day as a hydrochloride salt; i.p.; twice daily) dramatically inhibits retinal neovascularization in the mouse oxygen-induced retinopathy (OIR) model^[1].

Animal Model:	C57BL6/J mouse pups, oxygen-induced retinopathy (OIR) model^[1]
Dosage:	1.0, 2.5, or 5 g/kg per day
Administration:	Intraperitoneal injection, twice daily
Result:	Significantly decreased preretinal nuclei. Reduced neovascular tufts and vascular leakage in retinal vessels. Reduced preretinal neovascularization by 82% ± 7% and reduced VEGF mRNA by 64% ± 9% at 5 g/kg per day.

References

[1] Neu J, et al. The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3151-5. DOI:10.1167/iovs.05-1473

H-ARG-GLN-OH HYDROCHLORIDE SALT Preparation Products And Raw materials

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Preparation Products

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H-ARG-GLN-OH HYDROCHLORIDE SALT Suppliers

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2483-17-2, H-ARG-GLN-OH HYDROCHLORIDE SALTRelated Search:

H-ARG-ALA-NH2 2 HCL H-ARG-ASP-OH ACOH H-ARG-GLY-NH2 SULFATE H-ARG-ARG-ARG-OH ACETATE SALT H-ARG-ARG-OH ACETATE SALT H-ARG-ALA-OH ACOH H-ARG-D-ASP-OH H-ARG-ARG-ARG-ARG-OH H-ARG-ASN-NH2 SULFATE SALT H-ARG-GLU-OH H-ARG-GLY-OH HCL H-ARG-GLN-OH HYDROCHLORIDE SALT

H-ARG-GLN-OH HCL

H-ARG-GLN-OH HYDROCHLORIDE SALT

H-Arg-Gln-OH

L-Glutamine, L-arginyl-

(S)-5-Amino-2-((S)-2-amino-5-guanidinopentanamido)-5-oxopentanoic acid

Arg-Gln

Arginyl-Glutamine

2483-17-2