2-Methylcyclopentanone Property

Melting point:

-75°C

Boiling point:

139 °C (lit.)

Density 

0.917 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.435(lit.)

Flash point:

79 °F

storage temp. 

Inert atmosphere,2-8°C

form 

Liquid

color 

Clear colorless to very slightly yellow

Water Solubility 

soluble

InChIKey

ZIXLDMFVRPABBX-UHFFFAOYSA-N

LogP

0.690 (est)

CAS DataBase Reference

1120-72-5(CAS DataBase Reference)

NIST Chemistry Reference

Cyclopentanone, 2-methyl-(1120-72-5)

EPA Substance Registry System

2-Methylcyclopentanone (1120-72-5)

Safety

Hazard Codes 

F

Risk Statements 

10

Safety Statements 

16-29-33

RIDADR 

UN 1224 3/PG 3

WGK Germany 

3

HazardClass 

3.2

PackingGroup 

III

HS Code 

29142990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

2-Methylcyclopentanone Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

Uses

2-Methylcyclopentanone is a useful synthetic intermediate. It was used in the synthesis of MK-0354, a partial agonist of nicotinic acid and G-protein-coupled receptor 109a. It can also be used to prepare Falcipain inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 102, p. 190, 1980 DOI: 10.1021/ja00521a031
The Journal of Organic Chemistry, 38, p. 304, 1973 DOI: 10.1021/jo00942a022
Synthetic Communications, 8, p. 563, 1978 DOI: 10.1080/00397917808063587