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FOSFESTROL

Product Name
FOSFESTROL
CAS No.
522-40-7
Chemical Name
FOSFESTROL
Synonyms
FOSFESTROL;DIETHYLSTILBESTROL DIPHOSPHATE;DIETHYLSTILBOESTROLDIPHOSPHATE;diethylstilbestrol bisphosphate;diethylstilbesterol diphosphate;stilboestrol bis(dihydrogen phosphate);3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)];(E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate);alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate);alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol
CBNumber
CB6443874
Molecular Formula
C18H22O8P2
Formula Weight
428.31
MOL File
522-40-7.mol
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FOSFESTROL Property

Melting point:
250.5°C
storage temp. 
2-8°C
form 
solid
EPA Substance Registry System
Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, bis(dihydrogen phosphate) (522-40-7)
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific
Product number
059774
Product name
3-Hexene-3,4-diylbis(4,1-phenylene)bis[dihydrogen (phosphate)]
Packaging
500mg
Price
$199
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
SHG0000459
Product name
FOSFESTROL
Purity
95.00%
Packaging
1G
Price
$235.2
Updated
2021/12/16
AK Scientific
Product number
C563
Product name
Diethylstilbestroldiphosphate
Packaging
500mg
Price
$318
Updated
2021/12/16
Aronis compounds
Product number
BBC/528
Product name
3-hexene-3,4-diylbis(4,1-phenylene)bis[dihydrogen(phosphate)]
Packaging
5g
Price
$357
Updated
2021/12/16
Crysdot
Product number
CD61000642
Product name
(E)-Hex-3-ene-3,4-diylbis(4,1-phenylene)bis(dihydrogenphosphate)
Purity
95+%
Packaging
1g
Price
$772
Updated
2021/12/16
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FOSFESTROL Chemical Properties,Usage,Production

Originator

Stilphostrol,Dome,US,1955

Uses

Diethylstilbestrol Diphosphate USP (Stilphostrol) is used to treat Prostatic carcinoma.

Definition

ChEBI: Diethylstilbestrol diphosphate is an aryl phosphate. It is functionally related to a diethylstilbestrol.

Manufacturing Process

A solution of 1 part of α,α'-diethyl-4,4'-dihydroxystilbene in 5 parts of pyridine is added drop by drop to the strongly cooled solution of 2 parts of phosphorus-hydroxy chloride in 5 parts of pyridine. The mixture soon solidifies to a crystalline magma. It is allowed to stand in ice for ? hour and then for an hour at room temperature. The mass is then poured into an excess of saturated sodium bicarbonate solution. Unconsumed parent material is removed by extraction with ether. The aqueous solution is then mixed with 2 N hydrochloric acid, whereupon the primary phosphoric acid ester of α,α'- diethyl-4,4'-dihydroxystilbene of the formula is precipitated in the form of a voluminous white powder. By recrystallization or reprecipitation this ester may be further purified.

Therapeutic Function

Estrogen, Antitumor

General Description

Odorless off-white crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Organophosphates, such as FOSFESTROL, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for FOSFESTROL are not available; however, FOSFESTROL is probably combustible.

FOSFESTROL Preparation Products And Raw materials

Raw materials

Preparation Products

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FOSFESTROL Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Suzhou Unite pharmTech Co., Ltd ,
Tel
792-3901125 13222993784
Fax
0512-62575043
Email
sales@unite-pharm.com
Country
China
ProdList
296
Advantage
56
ATK CHEMICAL COMPANY LIMITED
Tel
021-51619050 13301662590
Fax
+86-21-51619052
Email
mandy@atkchemical.com
Country
China
ProdList
8025
Advantage
55
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3251
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34553
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15354
Advantage
58
Wuhan Ying Yuan Bei Biological Limited
Tel
13349903920 13349903920
Email
1540154086@qq.com
Country
China
ProdList
2995
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569266 15319487004
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
4084
Advantage
58
Harway Pharma CO., LTD
Tel
0546-5612566 13793982289
Fax
0546-5180666
Email
Lucy@harwaypharma.com
Country
China
ProdList
76
Advantage
58
Guangzhou Yunmen Biotechnology Co., Ltd
Tel
18902340307 18902340307
Fax
0751-2819901
Email
3356812514@qq.com
Country
China
ProdList
9245
Advantage
58
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View Lastest Price from FOSFESTROL manufacturers

Hebei Jiangkai Trading Co., Ltd
Product
[4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate 522-40-7
Price
US $35.00/G
Min. Order
1KG
Purity
98%Whatsapp;+8617197824028
Supply Ability
6000kg/week
Release date
2018-04-27

522-40-7, FOSFESTROLRelated Search:


  • FOSFESTROL
  • DIETHYLSTILBOESTROLDIPHOSPHATE
  • alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate)
  • alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol
  • diethylstilbesterol diphosphate
  • 3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)]
  • (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate)
  • [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate
  • stilboestrol bis(dihydrogen phosphate)
  • DIETHYLSTILBESTROL DIPHOSPHATE
  • diethylstilbestrol bisphosphate
  • Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, 1,1'-bis(dihydrogen phosphate)
  • (e)-4-(4-(4-(Phosphonooxy)phenyl)hex-3-en-3-yl)phenyl dihydrogen phosphate
  • 522-40-7
  • C18H22O8P2