BERTEROIN
- Product Name
- BERTEROIN
- CAS No.
- 4430-42-6
- Chemical Name
- BERTEROIN
- Synonyms
- KB47947;LP088984;KB-47947;LP-088984;BERTEROIN;OR-009512;1-isothiocyanato-5-(methylthio)pentane;5-(methylsulfanyl)pentyl isothiocyanate;1-isothiocyanato-5-methylsulfanylpentane;1-isothiocyanato-5-methylsulfanyl-pentane
- CBNumber
- CB6445272
- Molecular Formula
- C7H13NS2
- Formula Weight
- 175.31
- MOL File
- 4430-42-6.mol
BERTEROIN Property
- Melting point:
- 155～156℃
- Boiling point:
- 155 °C(Press: 10 Torr)
- Density
- 1.01±0.1 g/cm3(Predicted)
- FEMA
- 4416 | 5-(METHYLTHIO)PENTYL ISOTHIOCYANATE
- storage temp.
- Store at -20°C
- solubility
- DMF: 3 mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
- Odor
- at 0.01 % in propylene glycol. cabbage radish
- Odor Type
- radish
- JECFA Number
- 1896
- LogP
- 2.67
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 17880
- Product name
- Berteroin
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 17880
- Product name
- Berteroin
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $65
- Updated
- 2024/03/01
- Product number
- 17880
- Product name
- Berteroin
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $142
- Updated
- 2024/03/01
- Product number
- 17880
- Product name
- Berteroin
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $249
- Updated
- 2024/03/01
- Product number
- B318805
- Product name
- Berteroin
- Packaging
- 500mg
- Price
- $790
- Updated
- 2021/12/16
BERTEROIN Chemical Properties,Usage,Production
Description
Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. At 1.7 μM, it has been shown to double the phase II enzyme quinone reductase activity in mouse hepatoma cells. Berteroin exerts anti-inflammatory activity in LPS-stimulated RAW 264.7 macrophages, inhibiting degradation of IκBα, as well as NF-κB p65 translocation to the nucleus and DNA binding activity. It also suppresses IRAK degradation and phosphorylation of TAK1, p38 MAPK, ERK1/2, and Akt.
Chemical Properties
Pale yellow liquid; penetrating radish-like aroma
Occurrence
Reported found in radish and horseradish.
Uses
Berteroin is a compound with high odor potency occurring in horseradish ( Armoracia rusticana)
Definition
ChEBI: Berteroin is an isothiocyanate.
Aroma threshold values
High strength odor; recommend smelling in a 0.01% solution or less.
Enzyme inhibitor
This sulforaphane analogue and antimetastatic agent (FW = 175.43 g/mol; CAS 4430-42-6; Physical State = Liquid; Soluble in ethanol, DMSO, and chloroform; Store at -20° C; M.P. = 155-156° C), also named 5- methylthiopentyl isothiocyanate, is found in cruciferous vegetables (including Chinese cabbage and rucola leaves) and mustard oil. Berteroin inhibits LPS-induced degradation of Inhibitor of κBα (or IκBα) as well as NF-κB p65 translocation into the nucleus and DNA binding. Berteroin also suppresses degradation of IL-1 Receptor Associated Kinase and phosphorylation of Transforming Growth Factor β-Activated Kinase-1. Berteroin also inhibits LPS-induced phosphorylation of p38 MAPK, ERK1/2, and AKT
BERTEROIN Preparation Products And Raw materials
Raw materials
Preparation Products
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