ChemicalBook > CAS DataBase List > GGTI-298

GGTI-298

Product Name
GGTI-298
CAS No.
180977-44-0
Chemical Name
GGTI-298
Synonyms
CS-2228;GGTI-298;GGTI298 (GGTI-298;GGTI-298 free base;GGTI298 (CF3CO2H)salt;GGTI-298 trifluoroacetate salt;N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA;L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester;(S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate;N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT
CBNumber
CB6450528
Molecular Formula
C27H33N3O3S
Formula Weight
479.63
MOL File
Mol file
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GGTI-298 Property

Melting point:
99.5-100 °C
Boiling point:
673.7±55.0 °C(Predicted)
Density 
1.190±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: 22 mg/mL
form 
solid
pka
9.83±0.10(Predicted)
color 
off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2430
Product name
GGTI298
Purity
≥95%(HPLC)
Packaging
1
Price
$212
Updated
2021/12/16
Usbiological
Product number
255374
Product name
GGTI 298
Packaging
1mg
Price
$460
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611699
Product name
GGTI298
Packaging
5mg
Price
$555.9
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001112
Product name
GGTI-298
Purity
95.00%
Packaging
0.25MG
Price
$599.45
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611699
Product name
GGTI298
Packaging
1mg
Price
$306
Updated
2021/12/16
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GGTI-298 Chemical Properties,Usage,Production

Uses

GGTI 298 is a CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I (GGTase I). It has been shown to arrest human tumor cells and induce apoptosis.

Definition

ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)phenyl]-oxomethyl]amino]-4-methylpentanoic acid methyl ester is a leucine derivative.

GGTI-298 Preparation Products And Raw materials

Raw materials

Preparation Products

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GGTI-298 Suppliers

China 57 Japan 2 Switzerland 1 United Kingdom 2 United States 10 Global 72
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180977-44-0, GGTI-298Related Search:


  • GGTI-298
  • N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT
  • N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA
  • GGTI-298 trifluoroacetate salt
  • N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt
  • N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucinemethylestertrifluoroacetatesalt
  • GGTI298 (CF3CO2H)salt
  • CS-2228
  • GGTI298 (GGTI-298
  • methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate,2,2,2-trifluoroacetic acid
  • L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
  • GGTI-298 free base
  • (S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate
  • 180977-44-0
  • C27H33N3O3SC2HF3O2
  • C27H33N3O3SCF3CO2H
  • A cell-permeable, prodrug form of the GGTase I inhibitor GGTI-297.