2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID

Product Name: 2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID
CAS No.: 119959-65-8
Chemical Name: 2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID
Synonyms: N-ARACHIDONOYL TAURINE;N-Arachidonoyl Taurine Exclusive;2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID;Ethanesulfonic acid, 2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]-
CBNumber: CB6455578
Molecular Formula: C22H37NO4S
Formula Weight: 411.6
MOL File: Mol file

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2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Property

storage temp.: Store at -20°C
solubility: DMF: 10 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 1.5 mg/ml
form: A crystalline solid
color: Light yellow to brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10005537
Product name: N-Arachidonoyl Taurine
Purity: ≥98%
Packaging: 500μg
Price: $43
Updated: 2024/03/01

Cayman Chemical

Product number: 10005537
Product name: N-Arachidonoyl Taurine
Purity: ≥98%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 10005537
Product name: N-Arachidonoyl Taurine
Purity: ≥98%
Packaging: 5mg
Price: $332
Updated: 2024/03/01

Cayman Chemical

Product number: 10005537
Product name: N-Arachidonoyl Taurine
Purity: ≥98%
Packaging: 10mg
Price: $579
Updated: 2024/03/01

TRC

Product number: A765080
Product name: N-Arachidonoyltaurine
Packaging: 10mg
Price: $165
Updated: 2021/12/16

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2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Chemical Properties,Usage,Production

Description

N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC₅₀s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of Δ⁹-tetrahydrocannabinol (Δ⁹-THC).

Uses

N-Arachidonoyltaurine is a polyunsaturated lipid that inhibits the Cav3.3 current in T-type calcium channels.

Definition

ChEBI: A fatty acid-taurine conjugate derived from arachidonic acid.

IC 50

TRPV1: 28 μM (EC₅₀); TRPV4: 21 μM (Ki)

References

[1] MELISSA V. TURMAN. Oxidative Metabolism of a Fatty Acid Amide Hydrolase-Regulated Lipid, Arachidonoyltaurine[J]. Biochemistry Biochemistry, 2008, 47 12: 3917-3925. DOI: 10.1021/bi702530z
[2] DOMINIK P. WALUK . N-Acyl taurines trigger insulin secretion by increasing calcium flux in pancreatic β-cells[J]. Biochemical and biophysical research communications, 2013, 430 1: Pages 54-59. DOI: 10.1016/j.bbrc.2012.11.026
[3] EMMA LEISHMAN . Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult[J]. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018, 1863 5: Pages 479-492. DOI: 10.1016/j.bbalip.2018.02.001

2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Preparation Products And Raw materials

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2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID Suppliers

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View Lastest Price from 2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: N-Arachidonoyl Taurine 119959-65-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 5000KG
Release date: 2024-07-16

119959-65-8, 2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACIDRelated Search:

N-Arachidonoyl Taurine Exclusive

N-ARACHIDONOYL TAURINE

2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID

Ethanesulfonic acid, 2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]-

119959-65-8