ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE

Product Name: ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE
CAS No.: 31037-02-2
Chemical Name: ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE
Synonyms: ETHYL 5-AMINO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLATE;5-AMINO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;yrazole;AKOS B022231;Pyrazole aMine;ETHYL 5-AMINO-1;BUTTPARK 23\09-41;TIMTEC-BB SBB005505;ART-CHEM-BB B022231;ETHYL 5-AMINO-1-METHYL-1H-PYRAZOLE-4-CA&
CBNumber: CB6456469
Molecular Formula: C7H11N3O2
Formula Weight: 169.18
MOL File: 31037-02-2.mol

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ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE Property

Melting point:: 96-100 °C
Boiling point:: 121 °C(Press: 0.05 Torr)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
pka: 2.03±0.10(Predicted)
form: Crystals or Crystalline Powder
color: Yellow
λmax: 257nm(EtOH)(lit.)
Sensitive: Hygroscopic
BRN: 131200
InChI: InChI=1S/C7H11N3O2/c1-3-12-7(11)5-4-9-10(2)6(5)8/h4H,3,8H2,1-2H3
InChIKey: MEUSJJFWVKBUFP-UHFFFAOYSA-N
SMILES: N1(C)C(N)=C(C(OCC)=O)C=N1
CAS DataBase Reference: 31037-02-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-22
Safety Statements: 36/37/39-26-22-36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29331990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687197
Product name: Ethyl 5-amino-1-methyl-1H-pyrazole-4-carboxylate
Purity: 97%
Packaging: 5g
Price: $53.4
Updated: 2023/06/20

TCI Chemical

Product number: E0986
Product name: Ethyl 5-Amino-1-methylpyrazole-4-carboxylate
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $24
Updated: 2025/07/31

TCI Chemical

Product number: E0986
Product name: Ethyl 5-Amino-1-methylpyrazole-4-carboxylate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $72
Updated: 2025/07/31

TRC

Product number: E899563
Product name: Ethyl 5-Amino-1-methylpyrazole-4-carboxylate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: E899563
Product name: Ethyl 5-Amino-1-methylpyrazole-4-carboxylate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE Chemical Properties,Usage,Production

Chemical Properties

yellow crystals or crystalline powder

Uses

ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE features an amino group and a carboxylic acid moiety, which contribute to its reactivity and potential applications in various chemical reactions. The ethyl ester functional group enhances its solubility in organic solvents, making it useful in synthetic chemistry.

Synthesis

94-05-3

60-34-4

31037-02-2

Example A Synthesis of ethyl 5-amino-1-methyl-1H-pyrazole-4-carboxylate: methylhydrazine (8.6 mL, 162 mmol) was slowly added to a solution of ethyl (ethoxymethylene)cyanoacetate (24.9 g, 147 mmol) in ethanol (250 mL). The reaction mixture was heated to reflux and stirred continuously for 3 days. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting residue was purified by recrystallization from a mixed ethyl acetate/petroleum ether solvent to afford a white solid product identified as ethyl 5-amino-1-methyl-1H-pyrazole-4-carboxylate (21.1 g, 85% yield).

References

[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 19, p. 8670 - 8692
[2] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 17, p. 4585 - 4589
[3] Journal of Heterocyclic Chemistry, 2007, vol. 44, # 4, p. 749 - 755
[4] Patent: EP1512687, 2005, A1. Location in patent: Page/Page column 6
[5] Patent: US5498630, 1996, A

ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

5-AMINO-3-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 1-METHYL-4-ETHOXYCARBONYL PYRAZOLE-5-SULFONYL CHLORIDE Azimsulfuron 1-Methyl-4-Ethoxycarbonyl Pyrazole-5-Sulfonamide

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ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE Suppliers

Americas 1 Belgium 4 China 253 Europe 1 Germany 6 India 8 Japan 1 Russia 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 14 United States 47 Global 341

Changzhou hanergy Biotechnology Co., Ltd

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View Lastest Price from ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE 31037-02-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-16

Hebei Chuanghai Biotechnology Co,.LTD

Product: ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE 31037-02-2
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 1 ton
Release date: 2024-08-22

Shaanxi Dideu Medichem Co. Ltd

Product: ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE 31037-02-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-07-29

31037-02-2, ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATERelated Search:

5-AMINO-4-CARBETHOXY-1-PHENYLPYRAZOLE 5-AMINO-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 5-AMINO-1-(4-NITRO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE 1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID Ethyl pyrazole-4-carboxylate 1H-Pyrazole-4-carboxylicacid,5-amino-1-methyl-(9CI) 1-Methylpyrazole Pyrazole ETHYL 5-OXO-4,5-DIHYDROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBOXYLATE ETHYL 1-METHYL-5-(1H-PYRROL-1-YL)-1H-PYRAZOLE-4-CARBOXYLATE ethyl 5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate PYRAZOLE-4-CARBOXYLIC ACID, 3-AMINO-1-METHYL-, ETHYL ESTER ETHYL 5-AMINO-1-(4-FLUOROPHENYL)PYRAZOLE-4-CARBOXYLATE ETHYL 5-CHLOROPYRAZOLO[1,5-A]QUINAZOLINE-3-CARBOXYLATE ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-3-(2-HYDROXYETHOXY)-1H-PYRAZOLE-4-CARBOXYLATE BUTTPARK 138\40-73 ethyl 3-hydrazino-5-methyl-1H-pyrazole-4-carboxylate

5-AMINO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

AKOS B022231

TIMTEC-BB SBB005505

ETHYL 3-AMINO-2-METHYLPYRAZOLE-4-CARBOXYLATE

ETHYL 5-AMINO-1-METHYL-1H-PYRAZOLE-4-CA&

5-Amino-1-methyl-1H-pyrazole-4-carboxylicacideth

ethyl-5-amino-1-methyl-1Hpyrazole carboxylate

3-Amino-2-methyl-2H-pyrazole-4-carboxylic acid ethyl ester

Ethyl 5-amino-1-methylpyrazole-4-carboxylate,98%

yrazole

Pyrazole aMine

5-Amino-4-(ethoxycarbonyl)-1-methyl-1H-pyrazole

Ethyl 5-aMino-1-Methylpyrazole-4-carboxylate, 98% 1GR

Ethyl5-amino-1-methyl-1H-pyrazole-4-carboxylate,98%

-Amino-1-methylpyrazole-4-carboxylic acid ethyl ester

Ethyl 1-methyl-5-aminopyrazole-4-carboxylate

H-Pyrazole-4-carboxylic acid, 5-amino-1-methyl-, ethyl ester

thyl 3-amino-1-methylpyrazole-4-carboxylate

thyl 5-amino-1-methyl-4-pyrazolecarboxylate

yrazole-4-carboxylic acid, 5-amino-1-methyl-, ethyl ester

BUTTPARK 23\09-41

ART-CHEM-BB B022231

ETHYL 5-AMINO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLATE

ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE

5-AMino-1-Methyl-1H-pyrazole-4-carboxylic acid ethyl ester5-AMino-1-Methyl-1H-pyrazole-4-carboxylic acid ethyl ester

ethy1-5-amio-1-methy1-1H-pyrazole-4-carboxylate

Ethyl 5-amino-1-methyl-1<i>H</i>-pyrazole-4-carboxylate

1H-Pyrazole-4-carboxylic acid, 5-amino-1-methyl-, ethyl ester

ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLAT

Ethyl 5-amino-1-methyl-1H-pyrazole-4-carbo

ETHYL 5-AMINO-1

Ethyl5-Amino-1-methylpyrazole-4-carboxylate&gt

DETHYL 5-AMINO-1- METHYLPYRAZOLE-4- CARBOXYLATE

1H-Pyrazole-4-carboxylic acid, 5-amino-1-methyl-, ethyl ester (9CI, ACI)

5-amino-1-methyl-1H-Pyrazole-4-carboxylic acid ethyl ester (9CI ACI)

Ethyl 5-amino-1-methyl-1H-pyrazol-4-carboxylate

31037-02-2

313037-02-2

Pharmaceutical Intermediates

Pyrazole series

Esters

Pyrazoles & Triazoles

Heterocyclic Compounds

Pyrazoles & Triazoles

Building Blocks

Heterocyclic Building Blocks

Pyrazoles

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