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RP 001 (hydrochloride)

Product Name
RP 001 (hydrochloride)
CAS No.
1781880-34-9
Chemical Name
RP 001 (hydrochloride)
Synonyms
RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
CBNumber
CB64666596
Molecular Formula
C24H25ClN4O4
Formula Weight
468.94
MOL File
1781880-34-9.mol
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RP 001 (hydrochloride) Property

storage temp. 
Store at -20°C
solubility 
DMSO: 100 mM
form 
A solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16636
Product name
RP 001 (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
16636
Product name
RP 001 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
16636
Product name
RP 001 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$249
Updated
2024/03/01
Cayman Chemical
Product number
16636
Product name
RP 001 (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$530
Updated
2024/03/01
TRC
Product number
R700988
Product name
RP001Hydrochloride
Packaging
50mg
Price
$975
Updated
2021/12/16
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RP 001 (hydrochloride) Chemical Properties,Usage,Production

Description

RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 9 pM). It is competitive with W146 , a selective S1P1 antagonist, and induces internalization and polyubiquitination of S1P1 in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC50 = 0.03 mg/kg). It reduces S1P1-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.

Uses

RP 001 Hydrochloride is a picomolar, short-acting S1P1 agonist.

storage

Store at -20°C

RP 001 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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RP 001 (hydrochloride) Suppliers

China 6 United States 4 Global 10
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9804
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19699
Advantage
58
R&D Systems, Inc
Tel
18003437475 18003437475
Fax
1-612-656-4400
Email
rdname@qq.com
Country
China
ProdList
35733
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

1781880-34-9, RP 001 (hydrochloride)Related Search:


  • RP001 hydrochloride,RP 001 hydrochloride
  • N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
  • 1781880-34-9