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Linoleic Acid Alkyne

Product Name
Linoleic Acid Alkyne
CAS No.
1219038-31-9
Chemical Name
Linoleic Acid Alkyne
Synonyms
Linoleic Acid Alkyne;9(Z),12(Z)-octadecadien-17-ynoic acid;9,12-Octadecadien-17-ynoic acid, (9Z,12Z)-
CBNumber
CB64667018
Molecular Formula
C18H28O2
Formula Weight
276.41
MOL File
1219038-31-9.mol
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Linoleic Acid Alkyne Property

Boiling point:
393.8±37.0 °C(Predicted)
Density 
0.948±0.06 g/cm3(Predicted)
solubility 
0.15 M Tris-HCl pH 8.5: >1 mg/ml; DMF: > 100 mg/ml; DMSO: > 100 mg/ml; Ethanol: > 100 mg/ml; PBS (pH 7.2): <100 μg/ml
pka
4.78±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10541
Product name
Linoleic Acid Alkyne
Purity
≥98%
Packaging
100μg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
10541
Product name
Linoleic Acid Alkyne
Purity
≥98%
Packaging
500μg
Price
$220
Updated
2024/03/01
Cayman Chemical
Product number
10541
Product name
Linoleic Acid Alkyne
Purity
≥98%
Packaging
1mg
Price
$358
Updated
2024/03/01
Cayman Chemical
Product number
10541
Product name
Linoleic Acid Alkyne
Purity
≥98%
Packaging
5mg
Price
$1375
Updated
2024/03/01
AK Scientific
Product number
3388DF
Product name
(9Z,12Z)-Octadeca-9,12-dien-17-ynoicacid
Packaging
5mg
Price
$2415
Updated
2021/12/16
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Linoleic Acid Alkyne Chemical Properties,Usage,Production

Description

Linoleic acid alkyne is an ω-alkyne derivative of linoleic acid . The ω-alkyne moiety allows Cu(I)-catalyzed cycloaddition chemistry with other molecules containing an azide group.1,2 Linoleic acid alkyne has been used in experiments focusing on the biological roles of linoleic acid.3,4 Alternatively, this modified lipid can be used to synthesize other alkyne-containing products, such as glycerophospholipids, for click chemistry.5

References

1. Gaebler, A., Penno, A., Kuerschner, L., et al. A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins J. Lipid. Res. 57(10),1934-1947(2016).
2. Grammel, M., and Hang, H.C. Chemical reporters for biological discovery Nat. Chem. Biol. 9(8),475-484(2013).
3. Beavers, W.N., Serwa, R., Shimozu, Y., et al. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: Free radical and enzymatic oxidations J. Am. Chem. Soc. 136(32),11529-11539(2014).
4. Windsor, K., Genaro-Mattos, T.C., Kim, H.-Y.H., et al. Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome J. Lipid. Res. 54(10),2842-2850(2013).
5. Milne, S.B., Tallman, K.A., Serwa, R., et al. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry Nat. Chem. Biol. 6(3),205-207(2010).

Linoleic Acid Alkyne Preparation Products And Raw materials

Raw materials

Preparation Products

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Linoleic Acid Alkyne Suppliers

Alfa Chemistry
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1219038-31-9, Linoleic Acid AlkyneRelated Search:


  • Linoleic Acid Alkyne
  • 9(Z),12(Z)-octadecadien-17-ynoic acid
  • 9,12-Octadecadien-17-ynoic acid, (9Z,12Z)-
  • 1219038-31-9