SEMBL

Product Name: SEMBL
CAS No.: 1443448-82-5
Chemical Name: SEMBL
Synonyms: SEMBL;2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide;Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-;SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma- butyrolactone
CBNumber: CB64668499
Molecular Formula: C12H11NO4
Formula Weight: 233.22
MOL File: 1443448-82-5.mol

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SEMBL Property

Boiling point:: 536.7±50.0 °C(Predicted)
Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 8.29±0.30(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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SEMBL Chemical Properties,Usage,Production

Uses

SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer[1].

References

[1] Umezawa K, et al. Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin. Biochim Biophys Acta Proteins Proteom. 2020;1868(6):140412. DOI:10.1016/j.bbapap.2020.140412

SEMBL Preparation Products And Raw materials

Raw materials

Preparation Products

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SEMBL Suppliers

China 26 United States 2 Global 28

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1443448-82-5, SEMBLRelated Search:

SEMBL

Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-

SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma- butyrolactone

2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide

1443448-82-5