ChemicalBook > CAS DataBase List > UCB9608

UCB9608

Product Name
UCB9608
CAS No.
1616413-96-7
Chemical Name
UCB9608
Synonyms
CS-2884;UCB9608;UCB 9608;UCB9608;UCB9608, 10 mM in DMSO;Phosphatidylinositol 4 kinases,UCB-9608,Inhibitor,UCB 9608,UCB9608,PI4 kinases,PI4K,inhibit;6-amino-4-{4-[(4-methoxy-2-methylphenyl)carbamyl]-2-(S)-methylpiperazin-1-yl}-1-methylpyrazolo[3,4-d]pyrimidine;(S)-4-(6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methylpiperazine-1-carboxamide;(3S)-4-(6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-1-piperazinecarboxamide;1-Piperazinecarboxamide, 4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-, (3S)-
CBNumber
CB64668626
Molecular Formula
C20H26N8O2
Formula Weight
410.47
MOL File
1616413-96-7.mol
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UCB9608 Property

Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
13.36±0.70(Predicted)
color 
White to off-white
InChIKey
WRONAJQPZWDYAR-ZDUSSCGKSA-N
SMILES
N1(C(NC2=CC=C(OC)C=C2C)=O)CCN(C2N=C(N)N=C3N(C)N=CC3=2)[C@@H](C)C1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0047698
Product name
UCB9608
Purity
99.12%
Packaging
10mg
Price
$350
Updated
2021/12/16
Axon Medchem
Product number
Axon3005
Product name
UCB9608
Purity
99%
Packaging
2x25mg
Price
$814
Updated
2021/12/16
ChemScene
Product number
CS-0047698
Product name
UCB9608
Purity
99.12%
Packaging
50mg
Price
$1100
Updated
2021/12/16
ChemScene
Product number
CS-0047698
Product name
UCB9608
Purity
99.12%
Packaging
100mg
Price
$1650
Updated
2021/12/16
DC Chemicals
Product number
DC10928
Product name
UCB9608
Purity
>98%
Packaging
100mg
Price
$700
Updated
2021/12/16
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UCB9608 Chemical Properties,Usage,Production

Uses

UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. UCB9608 improves metabolic stability and exhibits excellent pharmacokinetic profile, acts as a potent immunosuppressive agent[1].

References

[1] Reuberson J, et al. Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. J Med Chem. 2018 Aug 9;61(15):6705-6723. DOI:10.1021/acs.jmedchem.8b00521

UCB9608 Preparation Products And Raw materials

Raw materials

Preparation Products

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UCB9608 Suppliers

Fujian boshi pharmaceutical technology co. LTD
Tel
0595-22008920; 18120708884
Email
393612455@qq.com
Country
China
ProdList
255
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4768
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29759
Advantage
68
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1944
Advantage
55
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Shanghai Yu Ben Biotechnology Co., Ltd.
Tel
021-61350663 15502154572
Fax
-
Email
1639466865@qq.com
Country
China
ProdList
498
Advantage
58

1616413-96-7, UCB9608Related Search:


  • UCB9608
  • 6-amino-4-{4-[(4-methoxy-2-methylphenyl)carbamyl]-2-(S)-methylpiperazin-1-yl}-1-methylpyrazolo[3,4-d]pyrimidine
  • CS-2884
  • UCB 9608;UCB9608
  • 1-Piperazinecarboxamide, 4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-, (3S)-
  • (3S)-4-(6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-1-piperazinecarboxamide
  • Phosphatidylinositol 4 kinases,UCB-9608,Inhibitor,UCB 9608,UCB9608,PI4 kinases,PI4K,inhibit
  • (S)-4-(6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methylpiperazine-1-carboxamide
  • UCB9608, 10 mM in DMSO
  • 1616413-96-7
  • C20H26N8O2