ChemicalBook > CAS DataBase List > Risdiplam

Risdiplam

Product Name
Risdiplam
CAS No.
1825352-65-5
Chemical Name
Risdiplam
Synonyms
RG7916;2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one;Lispran;RO7034067;Risdiplam;Risdiplam (RG7916);Risdiplam (RG-7916, RO-7034067);7-amino-2,3-dihydro-1H-inden-4-ol;RG 7916,Inhibitor,RG-7916,Risdiplam,RO 7034067,DNA/RNA Synthesis,RO-7034067,inhibit;7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one
CBNumber
CB64674494
Molecular Formula
C22H23N7O
Formula Weight
401.46
MOL File
1825352-65-5.mol
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Risdiplam Property

Density 
1.50±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO
pka
9.41±0.20(Predicted)
form 
solid
color 
Light yellow to yellow
InChI
InChI=1S/C22H23N7O/c1-14-9-18(26-29-11-15(2)24-21(14)29)17-10-20(30)28-12-16(3-4-19(28)25-17)27-8-7-23-22(13-27)5-6-22/h3-4,9-12,23H,5-8,13H2,1-2H3
InChIKey
ASKZRYGFUPSJPN-UHFFFAOYSA-N
SMILES
C12C=CC(N3CC4(CC4)NCC3)=CN1C(=O)C=C(C1=NN3C=C(C)N=C3C(C)=C1)N=2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
25mg
Price
$353
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
10mg
Price
$213
Updated
2024/03/01
ChemScene
Product number
CS-0039501
Product name
Risdiplam
Purity
99.35%
Packaging
10mg
Price
$250
Updated
2021/12/16
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Risdiplam Chemical Properties,Usage,Production

Description

Risdiplam is a survival of motor neuron 2 (SMN2) splicing modifier.

Chemical Properties

light yellow powder to yellow powder

Uses

Risdiplam is used in preparation of Imidazopyridazinyl Pyridopyrimidinones for treating spinal muscular atrophy. Gene splicing modulator.

Side effects

Body aches or pain, chest pain or tightness, chills, cough, ear congestion, fever, headache, loss of voice, runny or stuffy nose, sneezing, sore throat, trouble breathing, unusual tiredness or weakness and so on.

storage

0-4℃ for short term (days to weeks) or -20℃ for long term (months)

Risdiplam Preparation Products And Raw materials

Raw materials

Preparation Products

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Risdiplam Suppliers

China 131 India 1 United States 6 USA 1 Global 139
Zhengzhou Converging Chemical Co. LTD
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0371-0371-53399770 18037166334
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Shanghai Changyu Medical Technology Co. Ltd.
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Xuzhou Maikai Biotechnology Co., Ltd.
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Jilin Lianben Technology Development Co., Ltd
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Biopole Pharmatech Co., Ltd.
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Jinan Good Medical &Technology Ltd Co.,
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Chembest Research Laboratories Limited
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Wellman Pharmaceutical Group Limited
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Abydos Scientific
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Fan De(Beijing) Biotechnology Co., Ltd.
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Finetech Industry Limited
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Zhejiang J&C Biological Technology Co.,Limited
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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View Lastest Price from Risdiplam manufacturers

Jinan Good Medical Technology Co.,Ltd
Product
Risdiplam 1825352-65-5
Price
US $0.00/g
Min. Order
5g
Purity
99%
Supply Ability
10, 000grams
Release date
2024-09-03
Apeloa production Co.,Limited
Product
Risdiplam 1825352-65-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000
Release date
2024-06-05
Hebei Yanxi Chemical Co., Ltd.
Product
Risdiplam 1825352-65-5
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-08

1825352-65-5, RisdiplamRelated Search:


  • 7-amino-2,3-dihydro-1H-inden-4-ol
  • Risdiplam
  • RO7034067
  • RG7916
  • 4H-Pyrido[1,2-a]pyrimidin-4-one, 7-(4,7-diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-
  • 2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
  • Risdiplam (RG-7916, RO-7034067)
  • RG 7916,Inhibitor,RG-7916,Risdiplam,RO 7034067,DNA/RNA Synthesis,RO-7034067,inhibit
  • 2-(4,6-dimethylpyrrolo[1,2-b]pyridazin-2-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
  • 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one
  • Risdiplam (RG7916)
  • Lispran
  • 1825352-65-5
  • 1825352-65-6