ChemicalBook > CAS DataBase List > AurkinA
AurkinA
- Product Name
- AurkinA
- CAS No.
- 1534060-58-6
- Chemical Name
- AurkinA
- Synonyms
- AurkinA;2-(3-Bromophenyl)-8-fluoro-4-quinolinecarboxylicacid;4-Quinolinecarboxylic acid, 2-(3-bromophenyl)-8-fluoro-
- CBNumber
- CB64718589
- Molecular Formula
- C16H9BrFNO2
- Formula Weight
- 346.15
- MOL File
- 1534060-58-6.mol
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AurkinA Property
- Boiling point:
- 490.6±45.0 °C(Predicted)
- Density
- 1.610±0.06 g/cm3(Predicted)
- pka
- 2.12±0.10(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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AurkinA Chemical Properties,Usage,Production
Uses
Aurkin A is an allosteric inhibitor for the interaction between Aurora A Kinase (also known also Aurka) and TPX2, through targeting the TPX2 binding sites with Kd of 3.77 μM [1].
IC 50
Aurora A: 3.77 μM (Kd)
References
[1] Janeek M, et al., Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2. Sci Rep. 2016 Jun 24;6:28528. DOI:10.1038/srep28528
AurkinA Preparation Products And Raw materials
Raw materials
Preparation Products
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AurkinA Suppliers
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29430
- Advantage
- 58
- Tel
- 020-13113998854 13113998854
- 1094589719@qq.com
- Country
- China
- ProdList
- 6045
- Advantage
- 58