ChemicalBook > CAS DataBase List > Mesendogen
Mesendogen
- Product Name
- Mesendogen
- CAS No.
- 864716-85-8
- Chemical Name
- Mesendogen
- Synonyms
- Mesendogen;Mesendogen, 10 mM in DMSO;1-[2-chloro-5-(trifluoromethyl)phenyl]-3-[4-(propan-2-yl)benzoyl]thiourea;N-((2-Chloro-5-(trifluoromethyl)phenyl)carbamothioyl)-4-isopropylbenzamide;N-({[2-Chloro-5-(trifluoromethyl)phenyl]amino}carbonothioyl)-4-isopropylbenzamide;Benzamide, N-[[[2-chloro-5-(trifluoromethyl)phenyl]amino]thioxomethyl]-4-(1-methylethyl)-
- CBNumber
- CB64718635
- Molecular Formula
- C18H16ClF3N2OS
- Formula Weight
- 400.85
- MOL File
- 864716-85-8.mol
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Mesendogen Property
- Density
- 1.362±0.06 g/cm3(Predicted)
- pka
- 8.61±0.70(Predicted)
- form
- Solid
- color
- White to off-white
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Mesendogen Chemical Properties,Usage,Production
Description
Mesendogen is a novel inhibitor of TRPM6, promoting mesoderm and definitive endoderm differentiation of human embryonic stem cells through alteration of magnesium homeostasis.
Uses
Mesendogen is a TRPM6 inhibitor. Mesendogen enhances the mesoderm and definitive endoderm (DE) differentiations of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). Mesendogen can be used for the research of magnesium homeostasis during early embryonic cell development[1].
References
[1] Geng Y, Feng B. Mesendogen, a novel inhibitor of TRPM6, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells through alteration of magnesium homeostasis. Heliyon. 2015 Dec 1;1(4):e00046.
Mesendogen Preparation Products And Raw materials
Raw materials
Preparation Products
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