ChemicalBook > CAS DataBase List > N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
- Product Name
- N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
- CAS No.
- 912569-84-7
- Chemical Name
- N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
- Synonyms
- S-methyl DM1;Smethyl DM1,S methyl DM1,S-methyl DM-1;N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine;Maytansine, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-;N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (>90%)
- CBNumber
- CB64718640
- Molecular Formula
- C36H50ClN3O10S
- Formula Weight
- 752.32
- MOL File
- 912569-84-7.mol
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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Property
- Melting point:
- >152°C (dec.)
- Boiling point:
- 936.9±65.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 9.82±0.70(Predicted)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Chemical Properties,Usage,Production
Uses
N2''-Deacetyl-N2''-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
IC 50
Maytansinoids
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Preparation Products And Raw materials
Raw materials
Preparation Products
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