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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine

Product Name
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS No.
912569-84-7
Chemical Name
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
Synonyms
S-methyl DM1;Smethyl DM1,S methyl DM1,S-methyl DM-1;N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine;Maytansine, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-;N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (>90%)
CBNumber
CB64718640
Molecular Formula
C36H50ClN3O10S
Formula Weight
752.32
MOL File
912569-84-7.mol
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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Property

Melting point:
>152°C (dec.)
Boiling point:
936.9±65.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
9.82±0.70(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Chemical Properties,Usage,Production

Uses

N2''-Deacetyl-N2''-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.

IC 50

Maytansinoids

N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Preparation Products And Raw materials

Raw materials

Preparation Products

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N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine Suppliers

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912569-84-7, N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansineRelated Search:


  • N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
  • S-methyl DM1
  • N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (>90%)
  • Smethyl DM1,S methyl DM1,S-methyl DM-1
  • Maytansine, N2'-deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-
  • 912569-84-7