Quipazine dimaleate
- Product Name
- Quipazine dimaleate
- CAS No.
- 150323-78-7
- Chemical Name
- Quipazine dimaleate
- Synonyms
- 2-(Piperazin-1-yl)quinoline dimaleate;Quipazine dimaleate, 5-HT receptor agonist
- CBNumber
- CB64718655
- Molecular Formula
- C17H19N3O4
- Formula Weight
- 329.36
- MOL File
- 150323-78-7.mol
Quipazine dimaleate Property
- storage temp.
- Store at RT
- solubility
- DMSO: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 100 mM in water
N-Bromosuccinimide Price
- Product number
- Q797503
- Product name
- QuipazineDimaleate
- Packaging
- 100mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- B6383
- Product name
- Quipazinedimaleate
- Packaging
- 100mg
- Price
- $188
- Updated
- 2021/12/16
- Product number
- INB0001940
- Product name
- QUIPAZINE DIMALEATE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $280.35
- Updated
- 2021/12/16
Quipazine dimaleate Chemical Properties,Usage,Production
Uses
Quipazine Dimaleate is a 5-HT receptor agonist.
in vivo
Quipazine dimaleate (2.5, 5 and 7.5 mg/kg, one dose for once; i.p.) affects dietary self-selection of different macronutrient diets in male and female rats[1].
| Animal Model: | Male and female Wistar rats feed with different sources of the three macronutrients (Group 1: casein, corn starch, safflower oil. Group 2: egg protein, corn starch/sucrose, lard. Group S: casein hydrolysate, maltose dextrin, butter.)[1] |
| Dosage: | 2.5, 5 and 7.5 mg/kg |
| Administration: | Intraperitoneal injection; 2.5, 5 and 7.5 mg/kg, one dose for once |
| Result: | Increased water intake and food intake of male rats from Group S, and reduced food intake of female rats from Group 1 and Group 2s at 2h post-injection. Reduced food intake in female rats from Group 2, reduced protein intake in female rats from Group 1. |
storage
Store at RT
References
[1] R H P PORTER. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells[J]. British Journal of Pharmacology, 2009, 128 1: 13-20. DOI: 10.1038/sj.bjp.0702751
[2] G.B. SCHIAVI. Identification of serotonin 5-HT4 recognition sites in the porcine caudate nucleus by radioligand binding[J]. Neuropharmacology, 1994, 33 3: Pages 543-549. DOI: 10.1016/0028-3908(94)90085-x
[3] R. SAMANIN. Decrease of food intake by quipazine in the rat: relation to serotoninergic receptor stimulation[J]. Journal of Pharmacy and Pharmacology, 1977, 29 1: 53-54. DOI: 10.1111/j.2042-7158.1977.tb11241.x
[4] GRÉGOIRE COURTINE. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input[J]. Nature neuroscience, 2009, 12 10: 1333-1342. DOI: 10.1038/nn.2401
Quipazine dimaleate Preparation Products And Raw materials
Raw materials
Preparation Products
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