CX-157

Product Name: CX-157
CAS No.: 205187-53-7
Chemical Name: CX-157
Synonyms: CX-157;CX 157,CX157;3-Fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiine 10,10-dioxide;Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide
CBNumber: CB64797041
Molecular Formula: C14H8F4O4S
Formula Weight: 348.27
MOL File: 205187-53-7.mol

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CX-157 Property

Boiling point:: 430.0±45.0 °C(Predicted)
Density: 1.549±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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CX-157 Chemical Properties,Usage,Production

Uses

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

in vivo

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC₅₀ of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters^[1].

References

[1] Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31. DOI:10.1038/npp.2009.167

CX-157 Preparation Products And Raw materials

Raw materials

Preparation Products

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CX-157 Suppliers

China 7 United States 2 Global 9

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
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Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
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Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

205187-53-7, CX-157Related Search:

CX-157

Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide

CX 157,CX157

3-Fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiine 10,10-dioxide

205187-53-7

C14H8F4O4S