ChemicalBook > CAS DataBase List > L 888607

L 888607

Product Name
L 888607
CAS No.
860033-06-3
Chemical Name
L 888607
Synonyms
L 888607;1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1S)-
CBNumber
CB64797076
Molecular Formula
C19H15ClFNO2S
Formula Weight
375.84
MOL File
860033-06-3.mol
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L 888607 Property

Boiling point:
583.8±50.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 150 mg/mL (399.11 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
4.53±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0034796
Product name
L888607
Purity
99.88%
Packaging
5mg
Price
$320
Updated
2021/12/16
ChemScene
Product number
CS-0034796
Product name
L888607
Purity
99.88%
Packaging
10mg
Price
$520
Updated
2021/12/16
ChemScene
Product number
CS-0034796
Product name
L888607
Purity
99.88%
Packaging
25mg
Price
$1100
Updated
2021/12/16
ChemScene
Product number
CS-0034796
Product name
L888607
Purity
99.88%
Packaging
50mg
Price
$1700
Updated
2021/12/16
ChemScene
Product number
CS-0034796
Product name
L888607
Purity
99.88%
Packaging
100mg
Price
$2400
Updated
2021/12/16
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L 888607 Chemical Properties,Usage,Production

Uses

L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].

in vivo

L 888607 (i.v., 5 mg/kg, single or oral, 20 mg/kg, single) shows relative stability in vivo[1].

Animal Model:Male (ICR)BR mice[1]
Dosage:5 mg/kg, 20 mg/kg
Administration:i.v., 5 mg/kg, single or oral, 20 mg/kg, single
Result:Showed no obvious side effect.

IC 50

DP: 0.8 nM (Ki); TP Receptor: 283 nM (Ki); FP Receptor: 10018 nM (Ki); IP Receptor: 14434 nM (Ki)

References

[1] Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67(6):1834-9. DOI:10.1124/mol.104.009068

L 888607 Preparation Products And Raw materials

Raw materials

Preparation Products

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L 888607 Suppliers

China 11 United States 3 Global 14
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Beijing xinyanhui pharmaceutical research and development co., LTD
Tel
13969155946
Email
1461866103@qq.com
Country
China
ProdList
16111
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
5002
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58

860033-06-3, L 888607Related Search:


  • L 888607
  • 1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1S)-
  • 860033-06-3