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N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide

Product Name
N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide
CAS No.
1609389-52-7
Chemical Name
N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide
Synonyms
ACY-957, 10 mM in DMSO;6-Quinolinecarboxamide, N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-;N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide
CBNumber
CB64798482
Molecular Formula
C24H23N5OS
Formula Weight
429.54
MOL File
1609389-52-7.mol
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N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide Property

Boiling point:
602.7±55.0 °C(Predicted)
Density 
1.338±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 83.33 mg/mL (194.00 mM)
form 
Solid
pka
12.18±0.70(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0023625
Product name
ACY-957
Purity
99.91%
Packaging
50mg
Price
$1600
Updated
2021/12/16
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N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide Chemical Properties,Usage,Production

Uses

ACY-??957 is an orally selective inhibitor of HDAC1 and HDAC2 which may be useful in treatment of diseases such as cancer, HIV and sickle-cell anemia.

IC 50

HDAC1: 7 nM (IC50); HDAC2: 18 nM (IC50); HDAC3: 1300 nM (IC50)

N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide Suppliers

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1609389-52-7, N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamideRelated Search:


  • N-(2-amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide
  • 6-Quinolinecarboxamide, N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-
  • ACY-957, 10 mM in DMSO
  • 1609389-52-7