PKC-theta inhibitor
- Product Name
- PKC-theta inhibitor
- CAS No.
- 736048-65-0
- Chemical Name
- PKC-theta inhibitor
- Synonyms
- MDK-8650;PKC-theta inhibitor;PKC-theta inhibitor 2;N4-((4-(Aminomethyl)cyclohexyl)methyl)-5-nitro-N2-(2-(trifluoromethoxy)benzyl)pyrimidine-2,4-diamine;2,4-Pyrimidinediamine, N4-[[4-(aminomethyl)cyclohexyl]methyl]-5-nitro-N2-[[2-(trifluoromethoxy)phenyl]methyl]-
- CBNumber
- CB64809360
- Molecular Formula
- C20H25F3N6O3
- Formula Weight
- 454.45
- MOL File
- 736048-65-0.mol
PKC-theta inhibitor Property
- Boiling point:
- 597.1±60.0 °C(Predicted)
- Density
- 1.356±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 62.5 mg/mL (137.53 mM)
- form
- Solid
- pka
- 10.27±0.29(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0062613
- Product name
- PKC-thetainhibitor
- Purity
- 99.75%
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- CS-0062613
- Product name
- PKC-thetainhibitor
- Purity
- 99.75%
- Packaging
- 10mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- DC26157
- Product name
- PKC-thetainhibitor
- Purity
- >98%
- Packaging
- 1g
- Price
- $2200
- Updated
- 2021/12/16
PKC-theta inhibitor Chemical Properties,Usage,Production
Uses
PKC-theta inhibitor 2 is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1].
IC 50
PKCθ: 18 nM (IC50)
References
[1] Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30. DOI:10.1016/j.bmcl.2006.09.056
PKC-theta inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
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