ChemicalBook > CAS DataBase List > Y06036
Y06036
- Product Name
- Y06036
- CAS No.
- 1832671-96-1
- Chemical Name
- Y06036
- Synonyms
- Y06036;Y06036, 10 mM in DMSO;inhibit,Epigenetic Reader Domain,Inhibitor,Y-06036,Y 06036,Y06036;5-Bromo-2-methoxy-N-(6-methoxy-3-methylbenzo[d]isoxazol-5-yl)benzenesulfonamide;Benzenesulfonamide, 5-bromo-2-methoxy-N-(6-methoxy-3-methyl-1,2-benzisoxazol-5-yl)-
- CBNumber
- CB64818331
- Molecular Formula
- C16H15BrN2O5S
- Formula Weight
- 427.27
- MOL File
- 1832671-96-1.mol
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Y06036 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 130 mg/mL (304.26 mM)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0042275
- Product name
- Y06036
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0042275
- Product name
- Y06036
- Packaging
- 10mg
- Price
- $80
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0042275
- Product name
- Y06036
- Packaging
- 25mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0042275
- Product name
- Y06036
- Packaging
- 50mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0042275
- Product name
- Y06036
- Packaging
- 100mg
- Price
- $450
- Updated
- 2021/12/16
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Y06036 Chemical Properties,Usage,Production
Uses
Y06036 is CRPC inhibitor.
in vivo
Y06036 (50 mg/kg, i.p. injection, 5 times per week, 25 days) demonstrates therapeutic effects in a C4-2B CRPC xenograft tumor model in mice. Y06036 is well tolerated in the treated mice, based on the weight of the animal body and their general behavior[1].
| Animal Model: | Four-week-old male mice (strain: C.B-17/IcrHsd-Prkdcscid for C4-2B) with C4-2B mouse xenograft model[1] |
| Dosage: | 50 mg/kg, 100 μL |
| Administration: | Intraperitoneal (i.p.) injection, 5 times per week, 25 days |
| Result: | Exhibited strong antitumor activities during the 25-day treatment period, with a tumor growth inhibition (TGI) of 70%. |
IC 50
BRD4(1): 82 nM (Kd)
Y06036 Preparation Products And Raw materials
Raw materials
Preparation Products
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Y06036 Suppliers
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