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Gboxin

Product Name
Gboxin
CAS No.
2101315-36-8
Chemical Name
Gboxin
Synonyms
Gboxin;Gboxin chloride;Gboxin, 10 mM in DMSO;ATP Synthase,Gboxin,Inhibitor,inhibit,Mitochondrial Metabolism;gboxin N-(3-(Benzylamino)-1,4-dioxo-1,4-dihydronaphthalen-2- yl)-N-(4-fluorobenzyl)acetamide;2-Ethyl-1-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-3-methyl-1H-benzo[d]imidazol-3-ium chloride;2-ethyl-3-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-1-methyl-1H-benzo[d]imidazol-3-ium chloride
CBNumber
CB64844796
Molecular Formula
C22H33ClN2O2
Formula Weight
392.97
MOL File
2101315-36-8.mol
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Gboxin Property

storage temp. 
Store at -20°C
solubility 
DMF:10.0(Max Conc. mg/mL);25.45(Max Conc. mM)
DMSO:27.83(Max Conc. mg/mL);70.83(Max Conc. mM)
Ethanol:49.5(Max Conc. mg/mL);125.96(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);25.45(Max Conc. mM)
Water:6.0(Max Conc. mg/mL);15.27(Max Conc. mM)
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27861
Product name
Gboxin
Packaging
1mg
Price
$97
Updated
2024/03/01
Cayman Chemical
Product number
27861
Product name
Gboxin
Packaging
10mg
Price
$863
Updated
2024/03/01
Cayman Chemical
Product number
27861
Product name
Gboxin
Packaging
5mg
Price
$456
Updated
2024/03/01
ChemScene
Product number
CS-0089212
Product name
Gboxin
Purity
99.32%
Packaging
25mg
Price
$550
Updated
2021/12/16
Biosynth Carbosynth
Product number
BG168557
Product name
Gboxin NEW
Packaging
50mg
Price
$787.5
Updated
2021/12/16
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Gboxin Chemical Properties,Usage,Production

Uses

Gboxin is an oxidative phosphorylation (OXPHOS) inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity[1].

References

[1] Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346. DOI:10.1038/s41586-019-0993-x

Gboxin Preparation Products And Raw materials

Raw materials

Preparation Products

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2101315-36-8, GboxinRelated Search:


  • Gboxin
  • 2-ethyl-3-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-1-methyl-1H-benzo[d]imidazol-3-ium chloride
  • Gboxin chloride
  • gboxin N-(3-(Benzylamino)-1,4-dioxo-1,4-dihydronaphthalen-2- yl)-N-(4-fluorobenzyl)acetamide
  • ATP Synthase,Gboxin,Inhibitor,inhibit,Mitochondrial Metabolism
  • Gboxin, 10 mM in DMSO
  • 2-Ethyl-1-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-3-methyl-1H-benzo[d]imidazol-3-ium chloride
  • 2101315-36-8