LCL521
- Product Name
- LCL521
- CAS No.
- 1226851-11-1
- Chemical Name
- LCL521
- Synonyms
- LCL521;LCL521,LCL-521;(1R,2R)-1-(4-Nitrophenyl)-2-tetradecanamidopropane-1,3-diyl bis(2-(dimethylamino)acetate);Glycine, N,N-dimethyl-, 1,1'-[(1R,2R)-1-(4-nitrophenyl)-2-[(1-oxotetradecyl)amino]-1,3-propanediyl] ester
- CBNumber
- CB64844978
- Molecular Formula
- C31H52N4O7
- Formula Weight
- 592.77
- MOL File
- 1226851-11-1.mol
LCL521 Property
- Boiling point:
- 697.4±55.0 °C(Predicted)
- Density
- 1.093±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:150.0(Max Conc. mg/mL);253.05(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);168.7(Max Conc. mM) - form
- Oil
- pka
- 14.18±0.46(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H350May cause cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0028294
- Product name
- LCL521
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
- Product number
- orb573263
- Product name
- LCL521
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1802
- Updated
- 2021/12/16
- Product number
- CS-0028294
- Product name
- LCL521
- Packaging
- 100mg
- Price
- $2650
- Updated
- 2021/12/16
- Product number
- orb573263
- Product name
- LCL521
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3580.2
- Updated
- 2021/12/16
- Product number
- orb573263
- Product name
- LCL521
- Purity
- >98%
- Packaging
- 1g
- Price
- $7136.6
- Updated
- 2021/12/16
LCL521 Chemical Properties,Usage,Production
Uses
LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1].
References
[1] Bai A, et al. Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44. DOI:10.1016/j.bmc.2014.10.025
LCL521 Preparation Products And Raw materials
Raw materials
Preparation Products
LCL521 Suppliers
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