N-cyclopropene-L-Lysine

Product Name: N-cyclopropene-L-Lysine
CAS No.: 1610703-09-7
Chemical Name: N-cyclopropene-L-Lysine
Synonyms: N-cyclopropene-L-Lysine;cyclopropene – L - Lysine (CP);Click Amino Acid / cyclopropene – L - Lysine (CP);L-Lysine, N6-[[(2-methyl-2-cyclopropen-1-yl)methoxy]carbonyl]-;(2S)-2-Amino-6-[[[(2-methyl-2-cyclopropen-1-yl)methoxy]carbonyl]amino]hexanoic Acid
CBNumber: CB64849478
Molecular Formula: C12H20N2O4
Formula Weight: 256.3
MOL File: 1610703-09-7.mol

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N-cyclopropene-L-Lysine Property

Boiling point:: 452.1±40.0 °C(Predicted)
Density: 1.208±0.06 g/cm3(Predicted)
form: Solid
pka: 2.53±0.24(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-cyclopropene-L-Lysine Chemical Properties,Usage,Production

Uses

CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates[1][2].

References

[1] Oller-Salvia B. Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction. J Vis Exp. 2018 Sep 14;(139):58066. DOI:10.3791/58066
[2] Oller-Salvia B, et, al. Rapid and Efficient Generation of Stable Antibody-Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels-Alder Reaction. Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2831-2834. DOI:10.1002/anie.201712370

N-cyclopropene-L-Lysine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-cyclopropene-L-Lysine Suppliers

China 17 United States 1 Global 18

Changzhou Hopschain Chemical Co.,Ltd.

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Vicbio Biotechnology Co., Ltd.

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View Lastest Price from N-cyclopropene-L-Lysine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-Cyclopropene-L-Lysine 1610703-09-7
Price: US $0.00/mg
Min. Order: 25mg
Purity: >95.00%
Supply Ability: 25mg
Release date: 2024-03-21

1610703-09-7, N-cyclopropene-L-LysineRelated Search:

N-Pentyn1yloxycarbonyl]-L-lysine (2S)-2-amino-6-{[(prop-2-yn-1-yloxy)carbonyl]amino}hexanoic acid N-(4E)-TCO-L-lysine N-(2E)-TCO-L-lysine N-Cyclopropene-D-Mannopyranose-tetraacetated

N-cyclopropene-L-Lysine

Click Amino Acid / cyclopropene – L - Lysine (CP)

L-Lysine, N6-[[(2-methyl-2-cyclopropen-1-yl)methoxy]carbonyl]-

cyclopropene – L - Lysine (CP)

(2S)-2-Amino-6-[[[(2-methyl-2-cyclopropen-1-yl)methoxy]carbonyl]amino]hexanoic Acid

1610703-09-7

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