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INACTIN

Product Name
INACTIN
CAS No.
947-08-0
Chemical Name
INACTIN
Synonyms
inaktin;INACTIN;narkothion;brevinarcon;brevinarcone;venobarbital;Inactin? hydrate;Thiobutabarbital;thiobutabarbitonesodium;THIOBUTABARBITAL SODIUM
CBNumber
CB6486701
Molecular Formula
C10H15N2NaO2S
Formula Weight
250.29
MOL File
947-08-0.mol
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INACTIN Property

Melting point:
167-168 °C
solubility 
H2O: storage of solutions for more than 8 hours at 4°C is not recommended.soluble
form 
solid
color 
light yellow
PH
pH:9.0~11.0 (50g/l, 25℃)
EPA Substance Registry System
Thiobutabarbital sodium (947-08-0)
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Safety

WGK Germany 
3
RTECS 
CQ2278000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T133
Product name
Inactin? hydrate
Purity
≥98% (HPLC)
Packaging
1g
Price
$126
Updated
2024/03/01
Sigma-Aldrich
Product number
T133
Product name
Inactin? hydrate
Purity
≥98% (HPLC)
Packaging
5x1g
Price
$453
Updated
2024/03/01
Sigma-Aldrich
Product number
T133
Product name
Inactin? hydrate
Purity
≥98% (HPLC)
Packaging
25x1g
Price
$1630
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0004392
Product name
THIOBUTABARBITAL SODIUM SALT
Purity
95.00%
Packaging
100MG
Price
$1695.03
Updated
2021/12/16
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INACTIN Chemical Properties,Usage,Production

Description

Thiobutabarbital sodium , the sodium salt of 5-sec-butyl-5-ethylthiobarbituric acid, is a yellowishwhite amorphous powder soluble in water and alcohol. The colorless crystals of the free acid melt at 163 – 165 ?C. Thiobutabarbital is prepared from thiourea and a malonic ester .

Uses

Inactin? hydrate has been used to anesthetize rats to study stress-induced hypersensitivity and mice to study Cisplatin-induced neuropathy. It has also been used to anesthetize rats to measure the glomerular filtration rate (GFR).

General Description

Crystals.

Air & Water Reactions

Slight hygroscopic. Water soluble.

Reactivity Profile

An amine, organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data for INACTIN are not available. INACTIN is probably combustible.

Biochem/physiol Actions

Inactin? is a long-lasting rodent anesthetic with minimal effects on cardiovascular tone and renal output. It exhibits sedative and hypnotic properties.

Clinical Use

It is a short-acting intravenous anesthetic. It is the least potent of the thiobarbiturates and therefore causes the least number of complications during anesthesia. The compound is available as 5 % and 10 % solutions.

INACTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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INACTIN Suppliers

Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58

947-08-0, INACTINRelated Search:


  • 5-butan-2-yl-5-ethyl-2-sulfanylidenepyrimidin-3-ide-4,6-dione
  • 5-sec-butyl-5-ethyl-2-thiobarbituricacidsodiumsalt
  • 5-sec-butyl-5-ethyl-2-thio-barbituricacisodiumsalt
  • 6(1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylpropyl)-2-thioxo-mono
  • 5-Ethyl-5-[1-methylpropyl]-2-thiobarbituric acid, sodium salt
  • 4,6(1H,5H)-PyriMidinedione, 5-ethyldihydro-5-(1-Methylpropyl)-2-thioxo-, sodiuM salt
  • Inactin? hydrate
  • Thiobutabarbital sodium salt hydrate
  • brevinarcon
  • brevinarcone
  • inaktin
  • narkothion
  • thiobutabarbitonesodium
  • venobarbital
  • INACTIN
  • THIOBUTABARBITAL SODIUM
  • THIOBUTABARBITAL SODIUM SALT
  • 5-(sec-butyl)-5-ethyldihydro-2-thioxopyrimidine-4,6(1H,5H)-dione, monosodium salt
  • Thiobutabarbital
  • 947-08-0
  • C10H15N2NaO2S
  • C10H15N2O2SNa