TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
- Product Name
- TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
- CAS No.
- 871115-32-1
- Chemical Name
- TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
- Synonyms
- tert-Butyl 4-amino-4-(aminomethyl);N-BOC-4-amino-4-aminomethylpiperidine;1-Boc-4-aMino-4-aMinoMethylpiperidine;4-amino-4-aminomethyl-1-BOC-piperidine;1-N-Boc-4-amino-4-aminomethyl-piperidine;TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE;1-Piperidinecarboxylicacid, 4-amino-4-(aminomethyl)-, 1,1-di...;1-Piperidinecarboxylic acid, 4-aMino-4-(aMinoMethyl)-, 1,1-diMethylethyl ester
- CBNumber
- CB6490070
- Molecular Formula
- C11H23N3O2
- Formula Weight
- 229.32
- MOL File
- 871115-32-1.mol
TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE Property
- Boiling point:
- 326.4±27.0 °C(Predicted)
- Density
- 1.064±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 10.13±0.29(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C11H23N3O2/c1-10(2,3)16-9(15)14-6-4-11(13,8-12)5-7-14/h4-8,12-13H2,1-3H3
- InChIKey
- GFRZXIHYVYRFPV-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(N)(CN)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 119810
- Product name
- tert-Butyl 4-amino-4-(aminomethyl)-piperidine-1-carboxylate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $252
- Updated
- 2021/12/16
- Product number
- Y4413
- Product name
- tert-Butyl4-amino-4-(aminomethyl)piperidine-1-carboxylate
- Packaging
- 1g
- Price
- $371
- Updated
- 2021/12/16
- Product number
- 119810
- Product name
- tert-Butyl 4-amino-4-(aminomethyl)-piperidine-1-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $630
- Updated
- 2021/12/16
- Product number
- CHM0238069
- Product name
- TERT-BUTYL-4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
- Purity
- 98.00%
- Packaging
- 1G
- Price
- $1136.52
- Updated
- 2021/12/16
- Product number
- 119810
- Product name
- tert-Butyl 4-amino-4-(aminomethyl)-piperidine-1-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1764
- Updated
- 2021/12/16
TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
871115-22-9
871115-32-1
Tert-butyl 4-aminomethyl-4-(2,2,2-trifluoroacetamido)piperidine-1-carboxylate (400 mg, 1.2 mmol) was used as a raw material, which was dissolved in a mixed solution of MeOH/H2O (5/2, 5 mL) in 10% K2CO3 and the reaction was carried out at reflux overnight. Upon completion of the reaction, the reaction mixture was cooled to room temperature, followed by solvent evaporation. The residue was dissolved in ethyl acetate and washed sequentially with water and saturated saline. The organic layer was dried over anhydrous MgSO4, filtered and the solvent evaporated to afford 250 mg (91% yield) of the target product tert-butyl 4-amino-4-(aminomethyl)piperidine-1-carboxylate, which could be used in the subsequent reaction without further purification.1H NMR (400 MHz, CD3OD) δ 3.63-3.57 (m, 2H), 3.36 (s, 2H), 3.36-3.30 (s, 2H), 3.36-3.30 (s, 2H). 3.36-3.30 (m, 2H), 1.62-1.40 (m, 4H), 1.45 (s, 9H).
References
[1] Patent: US2005/277633, 2005, A1. Location in patent: Page/Page column 14
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 5, p. 1181 - 1184
[3] Patent: US2010/130506, 2010, A1. Location in patent: Page/Page column 112
[4] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 2519
TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE manufacturers
- Product
- TERT-BUTYL 4-AMINO-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE 871115-32-1
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2019-12-20