IMIDAPRILAT
- Product Name
- IMIDAPRILAT
- CAS No.
- 89371-44-8
- Chemical Name
- IMIDAPRILAT
- Synonyms
- 6366A;IMIDAPRILAT;Imidaprilate;Imidapril Diacid;Imidaprilate (6366A);(4S)-3-[(2S)-N-[(1S)-1-Carboxy-3-phenylpropyl]alanyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid;(S)-3-((S)-2-(((S)-1-carboxy-3-phenylpropyl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid;(4S)-3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid;(4S)-3-{(2S)-2-[N-((1S)-1-Carboxy-3-phenylpropyl)amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid;4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)-
- CBNumber
- CB6496850
- Molecular Formula
- C18H23N3O6
- Formula Weight
- 377.39
- MOL File
- 89371-44-8.mol
IMIDAPRILAT Property
- Melting point:
- 180-1820C
- alpha
- D19 -88.4° (c = 1 in 5% NaHCO3)
- Boiling point:
- 592.1±60.0 °C(Predicted)
- Density
- 1.356±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
- form
- Solid
- pka
- 2.17±0.10(Predicted)
- color
- White to Off-White
N-Bromosuccinimide Price
- Product number
- I275050
- Product name
- Imidaprilat
- Packaging
- 10mg
- Price
- $1940
- Updated
- 2021/12/16
- Product number
- API0000607
- Product name
- IMIDAPRILAT
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $649.95
- Updated
- 2021/12/16
- Product number
- 11106
- Product name
- Imidaprilat
- Packaging
- 1mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- API0000607
- Product name
- IMIDAPRILAT
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $2425.5
- Updated
- 2021/12/16
IMIDAPRILAT Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Uses
Antihypertensive.
Definition
ChEBI: Imidaprilat is a member of the class of imidazolidines that is imidapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of imidapril used to treat hypertension. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a drug metabolite. It is a dipeptide, a member of imidazolidines, a secondary amino compound, a dicarboxylic acid and a N-acylurea. It is functionally related to an imidapril.
in vivo
Imidaprilate (≥0.2 mg/kg) inhibits angiotensin I (AT-I)-induced pressor response. TA-6366 lowers the blood pressure in two-kidney one-clip renal hypertensive rats at 0.5-2 mg/kg via oral administration, and in spontaneously hypertensive rats (SHRs) at 2 to 10 mg/kg[1].
IMIDAPRILAT Preparation Products And Raw materials
Raw materials
Preparation Products
IMIDAPRILAT Suppliers
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from IMIDAPRILAT manufacturers
- Product
- Imidaprilat 89371-44-8
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98%
- Supply Ability
- 500mg
- Release date
- 2024-08-06