OSELTAMIVIR ACID

ChemicalBook > CAS DataBase List > OSELTAMIVIR ACID

Product Name: OSELTAMIVIR ACID
CAS No.: 187227-45-8
Chemical Name: OSELTAMIVIR ACID
Synonyms: Oseltamivir carboxylate;Oseltamivir impurity C;(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid;Gs4071;Gs 4071;Gs-4071;Aids095377;Aids-095377;Oseltamiviracid/GS4071;Oseltamivir acid, >=98%
CBNumber: CB6501589
Molecular Formula: C14H24N2O4
Formula Weight: 284.35
MOL File: 187227-45-8.mol

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OSELTAMIVIR ACID Property

Melting point:: 183-185°C
Boiling point:: 508.7±50.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: ≥14.2 mg/mL in DMSO; ≥46.1 mg/mL in H2O with gentle warming; ≥97 mg/mL in EtOH with gentle warming
pka: 4.13±0.60(Predicted)
EPA Substance Registry System: 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- (187227-45-8)

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Safety

HS Code: 9999999999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001340
Product name: Oseltamivir impurity C
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001340
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 15779
Product name: Oseltamivir Acid
Purity: ≥95%
Packaging: 500μg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 15779
Product name: Oseltamivir Acid
Purity: ≥95%
Packaging: 1mg
Price: $82
Updated: 2024/03/01

Cayman Chemical

Product number: 15779
Product name: Oseltamivir Acid
Purity: ≥95%
Packaging: 5mg
Price: $380
Updated: 2024/03/01

Cayman Chemical

Product number: 15779
Product name: Oseltamivir Acid
Purity: ≥95%
Packaging: 10mg
Price: $711
Updated: 2024/03/01

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OSELTAMIVIR ACID Chemical Properties,Usage,Production

Description

Oseltamivir (GS-4104) is an antiviral prodrug targeted against the influenza viruses. Oseltamivir acid is the active metabolite of oseltamivir. It acts as an inhibitor of influenza neuraminidases A and B (IC₅₀ = 0.1 to 4.9 nM for both enzymes), in this way preventing virus budding and release.

Chemical Properties

White Solid

Uses

Oseltamivir Acid (Oseltamivir EP Impurity C) is a metabolite of Oseltamivir (O701000). It is a COVID19-related research product.

Uses

Oseltamivir Acid is a metabolite of Oseltamivir (O701000).

Definition

ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). A antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza.

References

[1] enguang feng, deju ye, jian li, dengyou zhang, jinfang wang, fei zhao, rolf hilgenfeld, mingyue zheng, hualiang jiang and hong liu. recent advances in neuraminidase inhibitor development as anti-influenza drugs. chem med chem 2012, 7: 1527 – 1536.
[2] tom jefferson reviewer, mark jones, peter doshi, elizabeth a spencer, igho onakpoya, carl j heneghan. oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comment. bmj. 2014, 348: g2545.
[3] rashmi dixit, gulam khandaker, scott ilgoutz, harunor rashid and robert booy. emergence of oseltamivir resistance: control and management of influenza before, during and after the pandemic. infectious disorders – drug targets. 2013, 13 (1): 34-45.

OSELTAMIVIR ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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OSELTAMIVIR ACID Suppliers

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View Lastest Price from OSELTAMIVIR ACID manufacturers

Guangzhou PI PI BIOTECH INC

Product: Oseltamivir Impurity C (EP) 187227-45-8
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2020-05-31

Hangzhou Huarong Pharm Co., Ltd.

Product: (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid 187227-45-8
Price: US $0.00/mg
Min. Order: 10mg
Purity: 99%
Supply Ability: 10KG
Release date: 2021-09-14

Career Henan Chemical Co

Product: OSELTAMIVIR ACID 187227-45-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

187227-45-8, OSELTAMIVIR ACIDRelated Search:

3-Des(1-ethylpropoxy)-3-(1-Methylpropoxy) OseltaMivir 4-N-Desacetyl-5-N-acetyl OseltaMivir OseltaMivir IMpurity D OseltaMivir Acid Methyl Ester Oseltamivir EP Impurity A Oseltamivir EP Impurity E HCl ent-OseltaMivir Phosphate (3R,4R,5R)-3-(1-Ethylpropoxy)-4-hydroxy-5-[(Methylsulfonyl)oxy]-1-cyclohexene-1-carboxylic Acid Ethyl Ester Oseltamivir Impurity 17 Oseltamivir phosphate Oseltamivir OSELTAMIVIR MONO HYDROCHLORIDE OSELTAMIVIR ACID OSELTAMIVIR-D3 PHOSPHATE OSELTAMIVIR ACID-D3 OSELTAMIVIR, [3H]- OSELTAMIVIR CITRATE

(3R,4R,5S)-4-acetamido-5-amino-3

Oseltamivir Phosphate Impurity Ⅲ

(3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylic Acid

Oseltamivir Impurity C (EP)

Oseltamivir Carboxylic Acid HCl

GS 4071;RO 64-0802;OSELTAMIVIR CARBOXYLATE

(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid

(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohex-ene-1-carboxylic acid

1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)-

204255-11-8 (Monophospate salt)

Aids095377

Aids-095377

Gs 4071

Gs4071

Gs-4071

Oseltamivir carboxylate

OseltamivirCarboxylicAcid,4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylicAcid

OseltaMivir carboxylic acid

(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylic acid

Oseltamivir impurity C

Oseltamivir carboxylate (OC)

Oseltamivir acid, >=98%

Oseltamivir EP Impurity C

Oseltamivir carboxylate (OC),Metabolite of oseltamivir

(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid

Oseltamivir Phosphate impurity C (EP)

Oseltamivir Impurity 3 Monomer（Oseltamivir EP Impurity C Monomer）

Oseltamivir acid formate salt

Oseltamivir EP Impurity C (Oseltamivir Acid)

Oseltamivir carboxylate (GS 4071

Oseltamivir Impurity476

Oseltamivir carboxylic acidQ: What is Oseltamivir carboxylic acid Q: What is the CAS Number of Oseltamivir carboxylic acid Q: What is the storage condition of Oseltamivir carboxylic acid

Oseltamivir impurity C (Y0001340)Q: What is Oseltamivir impurity C (Y0001340) Q: What is the CAS Number of Oseltamivir impurity C (Y0001340)

Drug Metabolite,Inhibitor,Influenza Virus,Oseltamivir acid,GS4071,GS-4071,inhibit

Oseltamiviracid/GS4071

Oseltamivir Phosphate Impurity C

Oseltamivir Acid Impurity

187227-45-8

Various Metabolites and Impurities

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