(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE

Product Name: (D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE
CAS No.: 85286-38-0
Chemical Name: (D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE
Synonyms: thr(2)-thr(6)-;Enkephalin leu;DTLET, Deltakephalin;Lacosamide Impurity 62;(De-T 2) - Lou Nkepalin-T;[D-Thr2,Leu5]enkephalin-Thr;(D-Thr?)-Leu-Enkephalin-Thr;Enkephalin leu, thr(2)-thr(6)-;(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE;(D-THREONINE2)-LEUCINE ENKEPHALIN-THREONINE ACETATE)
CBNumber: CB6503422
Molecular Formula: C34H48N6O10
Formula Weight: 700.785
MOL File: 85286-38-0.mol

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(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE Property

Boiling point:: 1155.4±65.0 °C(Predicted)
Density: 1.303±0.06 g/cm3(Predicted)
pka: 3.25±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE Chemical Properties,Usage,Production

Uses

Deltakephalin is a potent, selective opiate δ-receptor agonist. Deltakephalin has analgesic properties[1].

in vivo

Deltakephalin (2 nM/rat; ICV; once) produces a pronounced analgesia in rats^[1].

Animal Model:	Male spontaneously hypertensive rats (SHR/n/Ibm) and male Wistar Albino Glaxo rats (WAG) (250-300 g)^[1]
Dosage:	2 nM/rat
Administration:	Intracerebroventrical injection
Result:	Produced pronounced analgesia in male spontaneously hypertensive rats with EC₅₀ values of 0.57 and 0.88 nM for the tail flick test and the tail compression test, respectively.

References

[1] Widy-Tyszkiewicz E, et, al. Analgesic activity of morphiceptin, beta-casomorphin-4, and deltakephalin in normotensive Wistar-Glaxo and spontaneously hypertensive rats. Peptides. 1989 May-Jun;10(3):539-44. DOI:10.1016/0196-9781(89)90139-3

(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE Suppliers

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85286-38-0, (D-THR2)-LEUCINE ENKEPHALIN-THR ACETATERelated Search:

(D-THR2)-LEUCINE ENKEPHALIN-THR ACETATE

(D-THREONINE2)-LEUCINE ENKEPHALIN-THREONINE ACETATE)

DTLET, Deltakephalin

[D-Thr2,Leu5]enkephalin-Thr

L-Threonine, L-tyrosyl-D-threonylglycyl-L-phenylalanyl-L-leucyl-

(D-Thr2)-Leu-Enkephalin-Thr H-Tyr-D-Thr-Gly-Phe-Leu-Thr-OH

Enkephalin leu

thr(2)-thr(6)-

Enkephalin leu, thr(2)-thr(6)-

(D-Thr?)-Leu-Enkephalin-Thr

(De-T 2) - Lou Nkepalin-T

Lacosamide Impurity 62

85286-38-0

C34H48N6O10