ChemicalBook > CAS DataBase List > RS 102895
RS 102895
- Product Name
- RS 102895
- CAS No.
- 300815-41-2
- Chemical Name
- RS 102895
- Synonyms
- 1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;RS 102895 HYDROCHLORIDE;CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-;1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE
- CBNumber
- CB6504368
- Molecular Formula
- C21H21F3N2O2
- Formula Weight
- 390.4
- MOL File
- 300815-41-2.mol
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RS 102895 Property
- Boiling point:
- 446.1±45.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Desiccate at RT
- solubility
- DMSO: 18 mg/mL, clear, colorless
- form
- powder
- pka
- 13.46±0.20(Predicted)
- color
- white
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- R1903
- Product name
- RS 102895 hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $241
- Updated
- 2024/03/01
Tocris
- Product number
- 2089
- Product name
- RS 102895 hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $162
- Updated
- 2021/12/16
Tocris
- Product number
- 2089
- Product name
- RS 102895 hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $682
- Updated
- 2021/12/16
Usbiological
- Product number
- 256510
- Product name
- RS 102895 hydrochloride
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0008334
- Product name
- RS 102895 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $345.45
- Updated
- 2021/12/16
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RS 102895 Chemical Properties,Usage,Production
Uses
RS 102895 is a CCR2-selective chemokine receptor inhibitor.
Biological Activity
CCR2-selective chemokine receptor antagonist (IC 50 values are 0.36 and 17.8 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC 50 values of 32 nM and 1.7 μ M respectively. Also inhibits α 1A , α 1D and 5-HT 1A receptors.
RS 102895 Preparation Products And Raw materials
Raw materials
Preparation Products
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RS 102895 Suppliers
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300815-41-2, RS 102895Related Search:
2,3-Dichloro-5-(trifluoromethyl)pyridine
2-fluoro-6-(trifluoroMethyl)benzene-1-sulfonyl chloride
Inter-trifluoromethyl iodobenzene
4-(2-AMINOPHENYL)-1-PHENETHYLPIPERIDINE
4-(O-AMINO-PHENYL) PIPERIDINE HYDROCHLORIDE
RS 102895
1-Phenethyl-4-phenyl-4-piperidinol
SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE