ChemicalBook > CAS DataBase List > Propargyl-PEG12-N3
Propargyl-PEG12-N3
- Product Name
- Propargyl-PEG12-N3
- CAS No.
- 2264091-72-5
- Chemical Name
- Propargyl-PEG12-N3
- Synonyms
- Alkyne-PEG12-N3;Propargyl-PEG12-N3;Azido-PEG12-propargyl;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yne, 1-azido-
- CBNumber
- CB65478242
- Molecular Formula
- C27H51N3O12
- Formula Weight
- 609.71
- MOL File
- 2264091-72-5.mol
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Propargyl-PEG12-N3 Chemical Properties,Usage,Production
Uses
Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014. DOI:10.1016/j.chembiol.2020.07.020
Propargyl-PEG12-N3 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl-PEG12-N3 manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Propargyl-PEG12-N3 2264091-72-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26