MSC1094308
- Product Name
- MSC1094308
- CAS No.
- 2219320-08-6
- Chemical Name
- MSC1094308
- Synonyms
- MSC1094308;MSC1094308,MSC-1094308;1H-Carbazole-3-methanamine, N-[4,4-bis(4-fluorophenyl)butyl]-6-fluoro-2,3,4,9-tetrahydro-;N-((6-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methyl)-4,4-bis(4-fluorophenyl)butan-1-amine;4,4-Bis(4-fluorophenyl)-N-[(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methyl]-1-butanamine
- CBNumber
- CB65544729
- Molecular Formula
- C29H29F3N2
- Formula Weight
- 462.55
- MOL File
- 2219320-08-6.mol
MSC1094308 Property
- Boiling point:
- 610.4±55.0 °C(Predicted)
- Density
- 1.211±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO: 2mg/mL, clear
- form
- Solid
- pka
- 16.91±0.40(Predicted)
- color
- Off-white to pink
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0086627
- Product name
- MSC1094308
- Purity
- 99.75%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-0086627
- Product name
- MSC1094308
- Purity
- 99.75%
- Packaging
- 10mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- CS-0086627
- Product name
- MSC1094308
- Purity
- 99.75%
- Packaging
- 50mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- CS-0086627
- Product name
- MSC1094308
- Purity
- 99.75%
- Packaging
- 100mg
- Price
- $1300
- Updated
- 2021/12/16
- Product number
- DC21352
- Product name
- MSC1094308
- Purity
- >98%
- Packaging
- 1g
- Price
- $4400
- Updated
- 2021/12/16
MSC1094308 Chemical Properties,Usage,Production
Biological Activity
MSC1094308 binding to drugable hotspot of p97 has the ability to block the D2 ATPase activity.', 'MSC1094308 is a reversible, non-ATP-competitive, type I AAA ATPase VPS4B-selective allosteric inhibitor (IC50 = 0.71 μM) with =10-fold reduced potency toward the type II AAA ATPase VCP/p97 and NSF (IC50 = 7.2 and >40 μM, respectively). MSC1094308 specifically inhibits p97-mediated Ub-GFP degradation without affecting proteasome-dependent ODD-luc degradation using a dual reporter HeLa cell line (10 μM) and exhibits comparable efficacy as DBeQ against 50 ng/mL TNFα-induced IKBα degradation in HeLa cells (10 μM).
MSC1094308 Preparation Products And Raw materials
Raw materials
Preparation Products
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