URAT1 inhibitor 1

Product Name: URAT1 inhibitor 1
CAS No.: 2268720-62-1
Chemical Name: URAT1 inhibitor 1
Synonyms: URAT1 inhibitor 1;URAT1 inhibitor 1,URAT-1 inhibitor 1;Methanesulfonamide, 1-[[5-bromo-4-[(4-bromo-1-naphthalenyl)methyl]-4H-1,2,4-triazol-3-yl]thio]-N-3-pyridinyl-
CBNumber: CB65821431
Molecular Formula: C19H15Br2N5O2S2
Formula Weight: 569.29
MOL File: 2268720-62-1.mol

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URAT1 inhibitor 1 Property

storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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URAT1 inhibitor 1 Chemical Properties,Usage,Production

Biological Activity

URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].

References

[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388.

URAT1 inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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URAT1 inhibitor 1 Suppliers

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2268720-62-1, URAT1 inhibitor 1Related Search:

URAT1 inhibitor 1

Methanesulfonamide, 1-[[5-bromo-4-[(4-bromo-1-naphthalenyl)methyl]-4H-1,2,4-triazol-3-yl]thio]-N-3-pyridinyl-

URAT1 inhibitor 1,URAT-1 inhibitor 1

2268720-62-1

C19H15Br2N5O2S2