SB 4
- Product Name
- SB 4
- CAS No.
- 100874-08-6
- Chemical Name
- SB 4
- Synonyms
- SB 4;SB 4 (Eticovo);BMP signaling agonist sb4;2-((4-Bromobenzyl)thio)benzo[d]oxazole;BMP signaling agonist sb4, 10 mM in DMSO;Benzoxazole, 2-[[(4-bromophenyl)methyl]thio]-;Inhibitor,SMAD,bmp,cell,inhibit,BMP signaling agonist sb4,BRE-luc,BMP signaling agonist sb 4,Transforming growth factor beta receptors,PREC,BMP signaling agonist sb-4,agonist,TGF-β Receptor
- CBNumber
- CB65830972
- Molecular Formula
- C14H10BrNOS
- Formula Weight
- 320.2
- MOL File
- 100874-08-6.mol
SB 4 Property
- Melting point:
- 70-72 °C
- Boiling point:
- 444.2±47.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 0.92±0.10(Predicted)
- color
- White to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 6881
- Product name
- SB4
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $78
- Updated
- 2021/12/16
- Product number
- CS-0087349
- Product name
- BMPsignalingagonistsb4
- Purity
- 99.89%
- Packaging
- 10mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- CS-0087349
- Product name
- BMPsignalingagonistsb4
- Purity
- 99.89%
- Packaging
- 50mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- CS-0087349
- Product name
- BMPsignalingagonistsb4
- Purity
- 99.89%
- Packaging
- 100mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- A1219194
- Product name
- 2-((4-Bromobenzyl)thio)benzo[d]oxazole
- Purity
- 98%
- Packaging
- 250mg
- Price
- $352
- Updated
- 2021/12/16
SB 4 Chemical Properties,Usage,Production
Uses
SB 4 (Eticovo) is a potent and selective agonist of bone morphogenetic protein 4 (BMP4) signaling.
Biological Activity
Sb4 is a cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist th at rapidly activate BMP in human renal cells (HEK293). Sb4 activates BMP by stabilization of intracellular p-SMAD-1/5/9. Apparently activation of the BMP pathway by sb4 cannot be reversed by inhibition of Noggin or type I BMP kinase inhibitors
storage
Store at -20°C
SB 4 Preparation Products And Raw materials
Raw materials
Preparation Products
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