5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL
- Product Name
- 5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL
- CAS No.
- 3004-42-0
- Chemical Name
- 5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL
- Synonyms
- HA-43;AKOS TOT-0317;AKOS TOT-0338;ASISCHEM Y91601;ASISCHEM Y67912;AKOS BBS-00007238;RARECHEM BG FB 0043;CHEMBRDG-BB 4012406;2-Phenyl-5-mercaptooxadiazole.;4-oxadiazole-5-thiol,2-phenyl-3
- CBNumber
- CB6665650
- Molecular Formula
- C8H6N2OS
- Formula Weight
- 178.21
- MOL File
- 3004-42-0.mol
5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL Property
- Melting point:
- 219-222 °C(lit.)
- Boiling point:
- 247℃
- Density
- 1.38
- refractive index
- 1.5690 (estimate)
- Flash point:
- 103℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.31±0.70(Predicted)
- form
- solid
- color
- Pale grey
- Water Solubility
- Soluble in water.
- CAS DataBase Reference
- 3004-42-0(CAS DataBase Reference)
- EPA Substance Registry System
- 1,3,4-Oxadiazole-2(3H)-thione, 5-phenyl- (3004-42-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- P320908
- Product name
- 5-Phenyl-1,3,4-oxadiazole-2-thiol
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- JK111777
- Product name
- 5-Phenyl-1,3,4-oxadiazole-2-thiol
- Purity
- 98%
- Packaging
- 25g
- Price
- $204
- Updated
- 2021/12/16
- Product number
- 036625
- Product name
- 5-Phenyl-1,3,4-oxadiazole-2-thiol
- Packaging
- 500mg
- Price
- $252
- Updated
- 2021/12/16
- Product number
- COR0003405
- Product name
- 5-PHENYL-1,3,4-OXADIAZOLE-2-THIOL
- Purity
- 95.00%
- Packaging
- 0.5G
- Price
- $460
- Updated
- 2021/12/16
- Product number
- COR0003405
- Product name
- 5-PHENYL-1,3,4-OXADIAZOLE-2-THIOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $505
- Updated
- 2021/12/16
5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL Chemical Properties,Usage,Production
Chemical Properties
slightly yellow crystalline powder
Synthesis
75-15-0
613-94-5
3004-42-0
General procedure for the synthesis of 5-phenyl-1,3,4-oxadiazole-2-thione from carbon disulfide and benzoylhydrazine: a mixture of benzoylhydrazine (0.41 g, 3 mmol), potassium phosphate (1.02 g, 3 mmol) and carbon disulfide (0.23 g, 3 mmol) in water (15 mL) was stirred at room temperature for 10 minutes. The reaction mixture was then heated to reflux for 2 hours. After completion of the reaction, the pH was adjusted to 7 with 1N HCl, the precipitated solid was filtered and dried in vacuum to afford 5-phenyl-1,3,4-oxadiazole-2-thione (0.51 g, 96%) as a white solid. Melting point: 197-199°C (literature value: 199-201°C).1H NMR (400MHz, CDCl3) δ10.52 (broad single peak, 1H), 7.93 (double peak, J=7.2Hz, 2H), 7.42-7.65 (multiple peaks, 3H).
References
[1] Tetrahedron, 2012, vol. 68, # 38, p. 7978 - 7983
[2] Patent: CN105837523, 2016, A. Location in patent: Paragraph 0020; 0024
[3] Patent: , 2016, . Location in patent: Paragraph 0018
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 3, p. 481 - 484
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 7, p. 1885 - 1889
5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL Preparation Products And Raw materials
Raw materials
Preparation Products
5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91