(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE

Product Name: (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
CAS No.: 148700-85-0
Chemical Name: (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
Synonyms: L 733060;L-733,060 hydrochlor;L-733,060 HYDROCHLORIDE;3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine;Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-;(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
CBNumber: CB6676120
Molecular Formula: C20H19F6NO
Formula Weight: 403.36
MOL File: 148700-85-0.mol

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(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Property

storage temp.: 2-8°C
solubility: DMSO: >10 mg/mL
form: solid
color: white

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0013970
Product name: L-733060
Purity: 95.00%
Packaging: 250MG
Price: $349.65
Updated: 2021/12/16

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(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Definition

ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines.

Biological Activity

A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Suppliers

China 10 Germany 2 Switzerland 1 United Kingdom 2 United States 3 Global 18

3B Pharmachem (Wuhan) International Co.,Ltd.

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148700-85-0, (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDERelated Search:

2-PHENYLPIPERIDINE (2R,3R)-3-([3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY)-2-PHENYLPIPERIDINE HYDROCHLORIDE (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE 3-(BENZYLOXY)PIPERIDINE

L-733,060 HYDROCHLORIDE

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE

3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine

L 733060

Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-

L-733,060 hydrochlor

148700-85-0

Tachykinin receptor