E4CPG

Product Name: E4CPG
CAS No.: 170846-89-6
Chemical Name: E4CPG
Synonyms: E4CPG;(RS)-α-Ethyl-4-carboxyphenylglycine;4-(1-amino-1-carboxypropyl)benzoic acid;(RS)-ALPHA-ETHYL-4-CARBOXYPHENYLGLYCINE;Benzeneacetic acid, α-amino-4-carboxy-α-ethyl-;Metabotropic glutamate receptors,metabotropic,Inhibitor,mGluR,mGluRs,inhibit,(RS)-ECPG,E4CPG,E-4CPG
CBNumber: CB6692522
Molecular Formula: C11H13NO4
Formula Weight: 223.23
MOL File: Mol file

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E4CPG Property

Boiling point:: 431.3±40.0 °C(Predicted)
Density: 1.337±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: H2O : < 0.1 mg/mL (insoluble)DMSO : < 1 mg/mL (insoluble or slightly soluble)
form: Powder
pka: 1.76±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E975105
Product name: E4CPG
Packaging: 25mg
Price: $230
Updated: 2021/12/16

Usbiological

Product number: 448042
Product name: E4CPG
Packaging: 10mg
Price: $396
Updated: 2021/12/16

Usbiological

Product number: 255213
Product name: E4CPG
Packaging: 10mg
Price: $403
Updated: 2021/12/16

ChemScene

Product number: CS-5703
Product name: E4CPG
Purity: ≥98.0%
Packaging: 5mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-5703
Product name: E4CPG
Purity: ≥98.0%
Packaging: 10mg
Price: $110
Updated: 2021/12/16

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E4CPG Chemical Properties,Usage,Production

Uses

E4CPG is a group I/group II metabotropic glutamate receptor antagonist.

in vivo

E4CPG (3-30 nmol/site (i.t.), 1-10 μmol/paw (i.pl.), and 1-10 nmol/site (i.c.v.)) significantly inhibits the nociception induced by the Glutamate-injection (i.pl.; 30 μmol/paw), and the maximal inhibition values for the antinociceptive action of E4CPG in Glutamate-induced nociception are 48% (i.pl.), 49% (i.t.) and 40% (i.c.v.) ^[4].
E4CPG (35 nM/3.5 μL, i.c.v.) completely blocks long-term depression (LTD) induced by the group I mGluR agonist Dihydroxyphenylglycine (DHPG, 100 nM/5 μL, i.c.v.) in male Sprague-Dawley rats^[5].

Animal Model:	Male Swiss mice (25-35 g)^[4]
Dosage:	3-30 nmol/site (i.t.), 1-10 μmol/paw (i.pl.) and 1-10 nmol/ site (i.c.v.)
Administration:	Single injection
Result:	The maximal inhibition values for the antinociceptive action of E4CPG in glutamate-induced nociception were 48% (i.pl.), 49% (i.t.) and 40% (i.c.v.).

Animal Model:	Male Sprague-Dawley rats^[5]
Dosage:	35 nM/3.5 μL
Administration:	Single injection, i.c.v.
Result:	Completely blocked LTD induced by the group I mGluR agonist dihydroxyphenylglycine (DHPG).

IC 50

mGluR

storage

Room temperature

E4CPG Preparation Products And Raw materials

Raw materials

Preparation Products

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E4CPG Suppliers

China 50 India 1 Japan 1 United Kingdom 2 United States 8 USA 1 Global 63

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
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Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
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Country: China
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EnliPharma Technology Co., Ltd

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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
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EMMX Biotechnology LLC

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Shanghai YuanYe Biotechnology Co., Ltd.

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ShangHai Biochempartner Co.,Ltd

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Country: China
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Musechem

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Angel Pharmatech, Ltd.

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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
Advantage: 58

170846-89-6, E4CPGRelated Search:

E4CPG

(RS)-ALPHA-ETHYL-4-CARBOXYPHENYLGLYCINE

(RS)-α-Ethyl-4-carboxyphenylglycine

4-(1-amino-1-carboxypropyl)benzoic acid

Benzeneacetic acid, α-amino-4-carboxy-α-ethyl-

Metabotropic glutamate receptors,metabotropic,Inhibitor,mGluR,mGluRs,inhibit,(RS)-ECPG,E4CPG,E-4CPG

170846-89-6

170846-69-6

Glutamate receptor