ChemicalBook > CAS DataBase List > H-TYR-LEU-OH

H-TYR-LEU-OH

Product Name: H-TYR-LEU-OH
CAS No.: 17355-10-1
Chemical Name: H-TYR-LEU-OH
Synonyms: YL;TYR-LEU;H-TYR-LEU-OH;tyrosylleucine;tyr-leucrystalline;L-TYROSYL-L-LEUCINE;L-Leucine, L-tyrosyl-;TYR-LEU 99% CRYSTALLINE;L-Leucine, N-L-tyrosyl-;(S)-2-((S)-2-AMino-3-(4-hydroxyphenyl)propanaMido)-4-Methylpentanoic acid
CBNumber: CB6704250
Molecular Formula: C15H22N2O4
Formula Weight: 294.35
MOL File: 17355-10-1.mol

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H-TYR-LEU-OH Property

Melting point:: 280 °C (sublm)(Solv: water (7732-18-5))
Boiling point:: 575.9±50.0 °C(Predicted)
Density: 1.218±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka: 3.12±0.10(Predicted)
form: Solid
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS110238
Product name: (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic acid
Purity: 95% ee
Packaging: 1g
Price: $199
Updated: 2021/12/16

Ark Pharm

Product number: AK-61100
Product name: (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoicacid
Purity: 95+%
Packaging: 5g
Price: $418
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0011072
Product name: (S)-2-((S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANAMIDO)-4-METHYLPENTANOIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $499.15
Updated: 2021/12/16

Activate Scientific

Product number: AS110238
Product name: (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic acid
Purity: 95% ee
Packaging: 5G
Price: $582
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0011072
Product name: (S)-2-((S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANAMIDO)-4-METHYLPENTANOIC ACID
Purity: 95.00%
Packaging: 1G
Price: $674
Updated: 2021/12/16

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H-TYR-LEU-OH Chemical Properties,Usage,Production

Uses

(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic Acid is a pharmaceutical agent with ACE inhibitory properties.

Definition

ChEBI: A dipeptide formed from L-tyrosine and L-leucine residues.

in vivo

Tyrosylleucine (YL), administered orally, intracerebroventricularly, or intraperitoneally exhibits a potent antidepressant-like activity in the forced swim and tail suspension tests in na ve mice^[1].

Animal Model:	Male ddY mice (24-27?g)^[1]
Dosage:	0.1-30?mg/kg, i.p.; 0.1-1.0 nmol/mouse, i.c.v.; 30-100?mg/kg, p.o.
Administration:	Administered orally, intracerebroventricularly, or intraperitoneally
Result:	Decreased immobility time after intraperitoneal (1-30?mg/kg) and intracerebroventricular (0.3-1 nmol/mouse) administrations in the FST. Exhibited a potent antidepressant-like activity in the forced swim and tail suspension tests in na?ve mice.

H-TYR-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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17355-10-1, H-TYR-LEU-OHRelated Search:

H-GLY-GLU-GLN-ARG-LYS-ASP-VAL-TYR-VAL-GLU-LEU-TYR-LEU-OH Boc-Tyr-Leu-OBzl Z-TYR-LEU-OH H-LEU-TYR-LEU-OH DADE-PY-L ARG-TYR-LEU-GLY-TYR-LEU-OH,H-ARG-TYR-LEU-GLY-TYR-LEU-OH H-TYR-TYR-LEU-OH H-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH H-TYR-LEU-OH PGLU-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH,PYR-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH AC-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-TYR-LEU-OH BIOTIN-LC-EPQ-PY-EEIPIYL H-TYR-LEU-OBZL HCL EPQ-PY-EEIPIYL* ILE-HIS-SER-ILE-SER-GLU-ARG-ILE-LEU-SER-THR-TYR-LEU H-PRO-CYS-HIS-ILE-ARG-GLN-ILE-ILE-ASN-THR-TRP-HIS-LYS-VAL-GLY-LYS-ASN-VAL-TYR-LEU-OH H-LEU-THR-VAL-TRP-GLY-THR-LYS-ASN-LEU-GLN-THR-ARG-VAL-THR-ALA-ILE-GLU-LYS-TYR-LEU-OH Z-TYR-LEU-OBZL

TYR-LEU

H-TYR-LEU-OH

L-TYROSYL-L-LEUCINE

TYR-LEU 99% CRYSTALLINE

tyr-leucrystalline

tyrosylleucine

L-Leucine, N-L-tyrosyl-

(S)-2-((S)-2-AMino-3-(4-hydroxyphenyl)propanaMido)-4-Methylpentanoic acid

L-Leucine, L-tyrosyl-

(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoic acid

17355-10-1

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