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5-ACETAMIDOINDOLE

Product Name
5-ACETAMIDOINDOLE
CAS No.
7145-71-3
Chemical Name
5-ACETAMIDOINDOLE
Synonyms
Nsc74979;5-ACETAMIDOINDOLE;N-(1H-indol-5-yl)acetaMide;Acetamide, N-1H-indol-5-yl-
CBNumber
CB6705000
Molecular Formula
C10H10N2O
Formula Weight
174.2
MOL File
7145-71-3.mol
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5-ACETAMIDOINDOLE Property

Melting point:
117-118 °C(Solv: acetonitrile (75-05-8))
Boiling point:
461.2±18.0 °C(Predicted)
Density 
1.290±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
15.59±0.43(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I628258
Product name
N-(1H-Indol-5-yl)acetamide
Packaging
100mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
OR931441
Product name
N-(1H-Indol-5-yl)acetamide
Purity
96%
Packaging
250mg
Price
$232
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0311825
Product name
5-ACETAMIDOINDOLE
Purity
95.00%
Packaging
5MG
Price
$502.84
Updated
2021/12/16
Apolloscientific
Product number
OR931441
Product name
N-(1H-Indol-5-yl)acetamide
Purity
96%
Packaging
1g
Price
$573
Updated
2021/12/16
Matrix Scientific
Product number
119652
Product name
N-(1H-Indol-5-yl)acetamide
Purity
95+%
Packaging
1g
Price
$576
Updated
2021/12/16
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5-ACETAMIDOINDOLE Chemical Properties,Usage,Production

Synthesis

5192-03-0

75-36-5

7145-71-3

General method (10): 5-Aminoindole (1.0 eq.) and triethylamine (3.6 eq.) were dissolved in dichloromethane (10 mL, corresponding to 1.182 mmol of raw material) and acetyl chloride (1.2 eq.) was added slowly. The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the mixture was poured into water and extracted three times with dichloromethane. The organic layers were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. Purification by fast silica gel column chromatography using 7:3 hexane/ethyl acetate as eluent afforded 5-acetamidoindole (Intermediate 17A/-(1/-/-indol-5-yl)acetamide, Intermediate 17) as a clear oil (177 mg, 1.016 mmol, 85% yield).1H NMR (400 MHz, CDCl3) δ 8.27 ( bs, 1H), 7.80 (s, 1H), 7.30 (d, J = 8.5 Hz, 2H), 7.20 (dd, J = 8.8, 2.0 Hz, 2H), 6.50 (s, 1H), 2.18 (s, 3H).

References

[1] Patent: WO2016/200339, 2016, A1. Location in patent: Page/Page column 93-94
[2] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 344 - 367

5-ACETAMIDOINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-ACETAMIDOINDOLE Suppliers

China 38 Germany 1 India 1 United Kingdom 1 United States 7 Global 48
Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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86-027-86697669
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sales@tcaschem.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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71826
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Amadis Chemical Company Limited
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571-89925085
Fax
0086-571-89925065
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sales@amadischem.com
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China
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131957
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Amatek Scientific Co. Ltd.
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0512-56316828
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0512-56316826
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info@amateksci.com
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China
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28785
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Biokitchen
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021-021-021-31663258 13795219287
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021-31663258
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donghuanwen@126.com
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Aikon International Limited
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025-58859352 18068836627
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02557626880
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sales01@aikonchem.com
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Shanghai Jizhi Biochemical Technology Co. Ltd.
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4009004166/18616739031 18616739031
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3007523370@qq.com
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52687
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Career Henan Chemica Co
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+86-0371-86658258 +8613203830695
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0371-86658258
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laboratory@coreychem.com
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China
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Wuxi Kehua Biological Technology Co., Ltd.
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0510-86838766 13636419861
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2258830676@qq.com
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Changzhou Kechem Bio-Scientific Co., LTD.
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sales@kechem.cn
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7145-71-3, 5-ACETAMIDOINDOLERelated Search:

Carzelesin Bizelesin Vat Brown 3 ADOZELESIN VAT BLACK 27 CHEMBRDG-BB 6085743 N-(2-METHYL-(1H)-INDOL-5-YL)-3-(TRIFLUOROMETHYL)BENZAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-THIOPHENE-2-CARBOXAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-4-(METHYLSULPHONYL)BENZAMIDE N-(1-ACETYLPIPERIDIN-4-YL)-N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-3,4,5-TRIMETHOXYBENZAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-4-[(TRIFLUOROMETHYL)SULPHONYL]BENZAMIDE N-(2-METHYL-(1H)-INDOL-5-YL)PROPANAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-3,4,5-TRIMETHOXYBENZAMIDE N-(1-ACETYLPIPERIDIN-4-YL)-N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)PROPANAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-4-(TRIFLUOROMETHYL)BENZAMIDE N-(2-METHYL-(1H)-INDOL-5-YL)THIOPHENE-2-CARBOXAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)-2,6-DICHLOROPYRIDINE-4-CARBOXAMIDE N-(2-TERT-BUTYL-(1H)-INDOL-5-YL)CYCLOPROPANECARBOXAMIDE

  • 5-ACETAMIDOINDOLE
  • Nsc74979
  • N-(1H-indol-5-yl)acetaMide
  • Acetamide, N-1H-indol-5-yl-
  • 7145-71-3