4-ISOPROPYLBENZYL CHLORIDE
- Product Name
- 4-ISOPROPYLBENZYL CHLORIDE
- CAS No.
- 2051-18-5
- Chemical Name
- 4-ISOPROPYLBENZYL CHLORIDE
- Synonyms
- Cuminyl chloride;AKOS BBS-00006741;7-CHLORO-P-CYMENE;p-cymene, 7-chloro-;p-(Chloromethyl)cumene;(contains ca. 10% o-form);4-ISOPROPYLBENZYL CHLORIDE;4-Isopropylbenzyl chloride 97%;4-Isopropylbenzyl Chloride 1-(CHLOROMETHYL)-4-ISOPROPYLBENZENE
- CBNumber
- CB6717421
- Molecular Formula
- C10H13Cl
- Formula Weight
- 168.66
- MOL File
- 2051-18-5.mol
4-ISOPROPYLBENZYL CHLORIDE Property
- Boiling point:
- 119 °C
- Density
- 1.5230 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.5230(lit.)
- Flash point:
- 206 °F
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- BRN
- 907207
- CAS DataBase Reference
- 2051-18-5(CAS DataBase Reference)
- EPA Substance Registry System
- 4-Isopropylbenzyl chloride (2051-18-5)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 1760 8/PG 3
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 2903.99.8001
- HazardClass
- 8
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309IF exposed or if you feel unwell:
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 563277
- Product name
- 4-Isopropylbenzyl chloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $46.4
- Updated
- 2022/05/15
- Product number
- I0225
- Product name
- 4-Isopropylbenzyl Chloride (contains ca. 10% o-form)
- Packaging
- 25G
- Price
- $99
- Updated
- 2025/07/31
- Product number
- I0225
- Product name
- 4-Isopropylbenzyl Chloride (contains ca. 10% o-form)
- Packaging
- 500G
- Price
- $584
- Updated
- 2025/07/31
- Product number
- 006628
- Product name
- 4-Isopropylbenzyl chloride
- Purity
- 98%
- Packaging
- 5g
- Price
- $37
- Updated
- 2021/12/16
- Product number
- 1700-5-65
- Product name
- 4-Isopropylbenzyl chloride
- Purity
- 98%
- Packaging
- 5G
- Price
- $44
- Updated
- 2021/12/16
4-ISOPROPYLBENZYL CHLORIDE Chemical Properties,Usage,Production
Uses
4-Isopropylbenzyl Chloride (CAS# 2051-18-5) can be used to reduce herbicidal damage.
Synthesis
122-03-2
2051-18-5
The general procedure for the synthesis of p-isopropylbenzyl chloride from 4-isopropylbenzaldehyde was as follows: 500 ml of methanol was added slowly and dropwise over a period of 5 h to 1000 ml of THF solution containing 148 g (1.0 mol) of 4-isopropylbenzaldehyde and 37.8 g (1.0 mol) of NaBH4 at 0-5 °C, while vigorous stirring was maintained. The reaction mixture was continued to be stirred at room temperature overnight, followed by evaporation of the solvent under vacuum. The residue was acidified to pH~1 with 1200 ml of 2M HCl solution, followed by extraction of the resulting (4-isopropylphenyl) methanol with 3 x 400 ml of dichloromethane. The organic extracts were combined, dried with Na2SO4 and evaporated to dryness. The resulting residue was dissolved in 1000 ml of dichloromethane and 73 ml (1.0 mol) of thionyl chloride was added slowly and dropwise at +5 °C. The reaction solution was stirred overnight at room temperature and evaporated to dryness and the residue was dissolved in 750 ml of dichloromethane. This solution was washed with 250 ml of water and after separating the organic layer, the aqueous layer was then extracted with 2 x 150 ml of dichloromethane. All organic extracts were combined, dried over Na2SO4, filtered through a short silica gel pad (40-63 μm) and finally evaporated to dryness. The crude product was distilled under vacuum to give 142 g (84% yield) of colorless liquid with a boiling point of 107-112°C/15 mmHg.
References
[1] Patent: WO2014/96282, 2014, A1. Location in patent: Page/Page column 54
4-ISOPROPYLBENZYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-ISOPROPYLBENZYL CHLORIDE Suppliers
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- Country
- Switzerland
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View Lastest Price from 4-ISOPROPYLBENZYL CHLORIDE manufacturers
- Product
- 4-Isopropylbenzyl Chloride 2051-18-5
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-01-13
- Product
- p-cymene, 7-chloro- 2051-18-5
- Price
- US $5.00-0.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-13
- Product
- 4-ISOPROPYLBENZYL CHLORIDE 2051-18-5
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2018-12-24