Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- Product Name
- Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- CAS No.
- 380843-81-2
- Chemical Name
- Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- Synonyms
- Desmethyl Bosutinib;Bosutinib Impurity 2 (N-Desmethyl Bosutinib);3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
- CBNumber
- CB67247990
- Molecular Formula
- C25H27Cl2N5O3
- Formula Weight
- 516.42
- MOL File
- 380843-81-2.mol
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Property
- Melting point:
- 123-125 °C
- Boiling point:
- 655.4±55.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- pka
- 9.19±0.10(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- D435305
- Product name
- 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
TRC
- Product number
- D435305
- Product name
- 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile
- Packaging
- 25mg
- Price
- $365
- Updated
- 2021/12/16
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Chemical Properties,Usage,Production
Uses
Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors.
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Preparation Products And Raw materials
Raw materials
Preparation Products
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