5-AMINO-4-FLUORO-2-METHYLPHENOL
- Product Name
- 5-AMINO-4-FLUORO-2-METHYLPHENOL
- CAS No.
- 122455-85-0
- Chemical Name
- 5-AMINO-4-FLUORO-2-METHYLPHENOL
- Synonyms
- 4-Amino-5-fluoro-o-cresol;5-AMINO-4-FLUORO-2-METHYLPHENOL;4-Amino-5-fluoro-o-methylphenol;3-Amino-4-fluoro-6-methylphenol;2-Methyl-4-fluoro-5-aminophenol;5-Amino-4-fluoro-o-cresol (OH=1);2-Fluoro-5-hydroxy-4-methylaniline;5-Amino-4-fluoro-2-methylphenol98%;5-Amino-4-fluoro-2-methylphenol 98%; Phenol,5-amino-4-fluoro-2-methyl-
- CBNumber
- CB6742627
- Molecular Formula
- C7H8FNO
- Formula Weight
- 141.14
- MOL File
- 122455-85-0.mol
5-AMINO-4-FLUORO-2-METHYLPHENOL Property
- Melting point:
- 147 °C
- Boiling point:
- 271.0±35.0 °C(Predicted)
- Density
- 1.275±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- crystalline powder
- pka
- 10.39±0.23(Predicted)
- color
- Reddish light brown
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC1996
- Product name
- 5-Amino-4-fluoro-2-methylphenol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $63
- Updated
- 2021/12/16
- Product number
- 4756-3-X0
- Product name
- 5-Amino-4-fluoro-2-methylphenol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $69
- Updated
- 2021/12/16
- Product number
- PC1996
- Product name
- 5-Amino-4-fluoro-2-methylphenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- PC1996
- Product name
- 5-Amino-4-fluoro-2-methylphenol
- Purity
- 98%
- Packaging
- 5g
- Price
- $331
- Updated
- 2021/12/16
- Product number
- 4756-3-X0
- Product name
- 5-Amino-4-fluoro-2-methylphenol
- Purity
- 98%
- Packaging
- 5G
- Price
- $365
- Updated
- 2021/12/16
5-AMINO-4-FLUORO-2-METHYLPHENOL Chemical Properties,Usage,Production
Synthesis
122455-84-9
122455-85-0
General procedure: a mixture of 4-fluoro-2-methyl-5-nitrophenol (1.4 g, 8.2 mmol) and 10% Pd/C (0.3 g, 20% w/w) in methanol (80 mL) was stirred for 2 hours under hydrogen atmosphere (30 psi). Upon completion of the reaction, the Pd/C catalyst was removed by filtration and the filtrate was concentrated to afford 5-amino-4-fluoro-2-methylphenol (0.68 g, 62% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 8.75 (s, 1H), 6.62 (d, J = 12.0 Hz, 1H), 6.21 (d, J = 8.1 Hz, 1H), 4.69 (s, 2H), 1.93 (s, 3H).
References
[1] Patent: WO2010/51373, 2010, A1. Location in patent: Page/Page column 69-70
[2] Journal of Medicinal Chemistry, 1999, vol. 42, # 26, p. 5369 - 5389
[3] Patent: US6362336, 2002, B1. Location in patent: Example 13
5-AMINO-4-FLUORO-2-METHYLPHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-AMINO-4-FLUORO-2-METHYLPHENOL manufacturers
- Product
- Phenol,5-amino-4-fluoro-2-methyl- 122455-85-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-09
- Product
- Phenol,5-amino-4-fluoro-2-methyl- 122455-85-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-09