ChemicalBook > CAS DataBase List > 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE

5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE

Product Name
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
CAS No.
40851-98-7
Chemical Name
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
Synonyms
5-chloro-3H-imidazo[4,5-b]pyridin-2-ol;5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H);5-Chloro-1H-iMidazo[4,5-b]pyridin-2(3H)-one;5-chloro-1H,2H,3H-iMidazo[4,5-b]pyridin-2-one;5-Chloro-1,3-dihydro-iMidazo[4,5-b]pyridin-2-one;5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE;2H-Imidazo[4,5-b]pyridin-2-one, 5-chloro-1,3-dihydro-
CBNumber
CB6754275
Molecular Formula
C6H4ClN3O
Formula Weight
169.57
MOL File
40851-98-7.mol
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5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Property

Density 
1.82
storage temp. 
2-8°C
form 
solid
pka
7.00±0.40(Predicted)
Appearance
Light brown to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC142316
Product name
5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
Packaging
100mg
Price
$61
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142316
Product name
5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
Packaging
250mg
Price
$122.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142316
Product name
5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
Packaging
500mg
Price
$210
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142316
Product name
5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
Packaging
1g
Price
$368.75
Updated
2021/12/16
AK Scientific
Product number
W6141
Product name
5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
Packaging
1g
Price
$377
Updated
2021/12/16
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5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Chemical Properties,Usage,Production

Synthesis

40851-95-4

32315-10-9

40851-98-7

The general procedure for the synthesis of 5-chloro-1H-imidazo[4,5-B]pyridin-2(3H)-one from 6-chloro-2,3-diaminopyridine and triphosgene was as follows: 0.143 g (1 mmol) of 6-chloro-pyridine-2,6-diamine was dissolved in 2 ml of methylene chloride, 0.4 g of sodium hydroxide dissolved in 2 ml of water was added to the solution, followed by 0.22 g of triphosgene dissolved in a a solution of 2 ml of dichloromethane. The reaction mixture was treated according to similar literature methods. Colorless crystal product was obtained by ethanol recrystallization. The yield was 0.08 g (0.47 mmol) in 47% yield with a melting point of 374°C. Infrared spectra (IR, cm-1): 3094, 3002, 2817, 1770. 1H NMR (200 MHz, DMSO-d6) δ (ppm): 11.58 (s, 1H, NH), 11.03 (s, 1H, NH), 7.27 (d, 1H, J=8.0 Hz, aromatic H), 7.01 (d, 1H, J= 8.1 Hz, aromatic H).13C NMR (50 MHz, DMSO-d6) δ (ppm): 154.20, 144.34, 139.82, 122.81, 117.08, 115.63.

References

[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 12, p. 3669 - 3677

5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Suppliers

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View Lastest Price from 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE 40851-98-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE 40851-98-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

40851-98-7, 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONERelated Search:


  • 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
  • 5-Chloro-1H-iMidazo[4,5-b]pyridin-2(3H)-one
  • 5-chloro-1H,2H,3H-iMidazo[4,5-b]pyridin-2-one
  • 5-Chloro-1,3-dihydro-iMidazo[4,5-b]pyridin-2-one
  • 2H-Imidazo[4,5-b]pyridin-2-one, 5-chloro-1,3-dihydro-
  • 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)
  • 5-chloro-3H-imidazo[4,5-b]pyridin-2-ol
  • 40851-98-7