5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
- Product Name
- 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
- CAS No.
- 40851-98-7
- Chemical Name
- 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE
- Synonyms
- 5-chloro-3H-imidazo[4,5-b]pyridin-2-ol;5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H);5-Chloro-1H-iMidazo[4,5-b]pyridin-2(3H)-one;5-chloro-1H,2H,3H-iMidazo[4,5-b]pyridin-2-one;5-Chloro-1,3-dihydro-iMidazo[4,5-b]pyridin-2-one;5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE;2H-Imidazo[4,5-b]pyridin-2-one, 5-chloro-1,3-dihydro-
- CBNumber
- CB6754275
- Molecular Formula
- C6H4ClN3O
- Formula Weight
- 169.57
- MOL File
- 40851-98-7.mol
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Property
- Density
- 1.82
- storage temp.
- 2-8°C
- form
- solid
- pka
- 7.00±0.40(Predicted)
- Appearance
- Light brown to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC142316
- Product name
- 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
- Packaging
- 100mg
- Price
- $61
- Updated
- 2021/12/16
- Product number
- FC142316
- Product name
- 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
- Packaging
- 250mg
- Price
- $122.5
- Updated
- 2021/12/16
- Product number
- FC142316
- Product name
- 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
- Packaging
- 500mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- FC142316
- Product name
- 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
- Packaging
- 1g
- Price
- $368.75
- Updated
- 2021/12/16
- Product number
- W6141
- Product name
- 5-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one
- Packaging
- 1g
- Price
- $377
- Updated
- 2021/12/16
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Chemical Properties,Usage,Production
Synthesis
40851-95-4
32315-10-9
40851-98-7
The general procedure for the synthesis of 5-chloro-1H-imidazo[4,5-B]pyridin-2(3H)-one from 6-chloro-2,3-diaminopyridine and triphosgene was as follows: 0.143 g (1 mmol) of 6-chloro-pyridine-2,6-diamine was dissolved in 2 ml of methylene chloride, 0.4 g of sodium hydroxide dissolved in 2 ml of water was added to the solution, followed by 0.22 g of triphosgene dissolved in a a solution of 2 ml of dichloromethane. The reaction mixture was treated according to similar literature methods. Colorless crystal product was obtained by ethanol recrystallization. The yield was 0.08 g (0.47 mmol) in 47% yield with a melting point of 374°C. Infrared spectra (IR, cm-1): 3094, 3002, 2817, 1770. 1H NMR (200 MHz, DMSO-d6) δ (ppm): 11.58 (s, 1H, NH), 11.03 (s, 1H, NH), 7.27 (d, 1H, J=8.0 Hz, aromatic H), 7.01 (d, 1H, J= 8.1 Hz, aromatic H).13C NMR (50 MHz, DMSO-d6) δ (ppm): 154.20, 144.34, 139.82, 122.81, 117.08, 115.63.
References
[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 12, p. 3669 - 3677
5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE manufacturers
- Product
- 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE 40851-98-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE 40851-98-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09